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Advanced filters: Author: Bruna Miglioranza Scavuzzi Clear advanced filters

Recovery from apoptosis in photoreceptor cells: A role for mitophagy

Bhavneet Kaur
Bruna Miglioranza Scavuzzi
David N. Zacks
ResearchOpen Access30 Jan 2026
Cell Death & Disease

P: 1-12
The lupus susceptibility allele DRB1*03:01 encodes a disease-driving epitope

In the presence of IFN-γ, a short DRB1*03:01-encoded allelic epitope is found to activate a characteristic lupus transcriptome in macrophages and trigger a cascade of systemic lupus erythematosus-associated cellular aberrations.

Bruna Miglioranza Scavuzzi
Vincent van Drongelen
Joseph Holoshitz
ResearchOpen Access28 Jul 2022
Communications Biology

Volume: 5, P: 1-15
HLA-DRB1 allelic epitopes that associate with autoimmune disease risk or protection activate reciprocal macrophage polarization

Vincent van Drongelen
Bruna Miglioranza Scavuzzi
Joseph Holoshitz
ResearchOpen Access28 Jan 2021
Scientific Reports

Volume: 11, P: 1-15

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Recovery from apoptosis in photoreceptor cells: A role for mitophagy

The lupus susceptibility allele DRB103:01* encodes a disease-driving epitope

HLA-DRB1 allelic epitopes that associate with autoimmune disease risk or protection activate reciprocal macrophage polarization

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Recovery from apoptosis in photoreceptor cells: A role for mitophagy

The lupus susceptibility allele DRB1*03:01 encodes a disease-driving epitope

HLA-DRB1 allelic epitopes that associate with autoimmune disease risk or protection activate reciprocal macrophage polarization

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The lupus susceptibility allele DRB103:01* encodes a disease-driving epitope