Nature Search

Infertility in female mice lacking the receptor for interleukin 11 is due to a defective uterine response to implantation

Lorraine Robb
Ruili Li
C. Glenn Begley
Research01 Mar 1998
Nature Medicine

Volume: 4, P: 303-308
Industry is more alarmed about reproducibility than academia

Anton Bespalov
Adrian G. Barnett
C. Glenn Begley
Correspondence28 Nov 2018
Nature

Volume: 563, P: 626
The CD2-scl transgene alters the phenotype and frequency of T-lymphomas in N-ras transgenic or p53 deficient mice

David J Curtis
Lorraine Robb
C Glenn Begley
Research11 Dec 1997
Oncogene

Volume: 15, P: 2975-2983
Six red flags for suspect work

C. Glenn Begley explains how to recognize the preclinical papers in which the data won't stand up.

C. Glenn Begley
Comments & Opinion22 May 2013
Nature

Volume: 497, P: 433-434
Robust research: Institutions must do their part for reproducibility

Tie funding to verified good institutional practice, and robust science will shoot up the agenda, say C. Glenn Begley, Alastair M. Buchan and Ulrich Dirnagl.

C. Glenn Begley
Alastair M. Buchan
Ulrich Dirnagl
Comments & Opinion01 Sept 2015
Nature

Volume: 525, P: 25-27
Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability

Endothelial to mesenchymal transition (EndMT) is a crucial developmental process that also plays a role in the pathogenesis of some diseases. Here the authors show that EndMT contributes to the development of atherosclerosis in mice and humans, and is associated with complex human plaques that may be prone to rupture.

Solene M. Evrard
Laura Lecce
Jason C. Kovacic
ResearchOpen Access24 Jun 2016
Nature Communications

Volume: 7, P: 1-16
Expression and function of members of the cytokine receptor superfamily on breast cancer cells

Andrea M Douglas
Geraldine A Goss
C Glenn Begley
Research13 Feb 1997
Oncogene

Volume: 14, P: 661-669
Raise standards for preclinical cancer research

C. Glenn Begley and Lee M. Ellis propose how methods, publications and incentives must change if patients are to benefit.

C. Glenn Begley
Lee M. Ellis
Comments & Opinion28 Mar 2012
Nature

Volume: 483, P: 531-533
Reproducibility: Standardize antibodies used in research

To save millions of dollars and dramatically improve reproducibility, protein-binding reagents must be defined by their sequences and produced as recombinant proteins, say Andrew Bradbury, Andreas Plückthun and 110 co-signatories.

Andrew Bradbury
Andreas Plückthun
Comments & Opinion04 Feb 2015
Nature

Volume: 518, P: 27-29
The PIM-1 serine kinase prolongs survival and inhibits apoptosis-related mitochondrial dysfunction in part through a bcl-2-dependent pathway

Michael Lilly
Jouko Sandholm
Andrew Kraft
Research14 Jul 1999
Oncogene

Volume: 18, P: 4022-4031
Genome-wide association study identifies novel breast cancer susceptibility loci

Previous work has identified several genes where mutations lead to breast cancer, but other genetic and environmental factors must still be accounted for. A large study of genetic association with breast cancer points to four novel genes and many more genetic markers that should be pursued for their link to cancer susceptibility.

Douglas F. Easton
Karen A. Pooley
Bruce A. J. Ponder
Research28 Jun 2007
Nature

Volume: 447, P: 1087-1093
An unexpected biochemical and functional interaction between gp130 and the EGF receptor family in breast cancer cells

Susan L Grant
Annet Hammacher
C Glenn Begley
Research24 Jan 2002
Oncogene

Volume: 21, P: 460-474
Endothelial CXCR7 regulates breast cancer metastasis

A C Stacer
J Fenner
G D Luker
Research29 Jun 2015
Oncogene

Volume: 35, P: 1716-1724
Unleashing the power of inhibitors of oncogenic kinases through BH3 mimetics

Can combining oncogenic kinase inhibitors with direct activators of the apoptosis machinery, such as the BH3 mimetic ABT-737, produce durable clinical responses in patients with cancer?

Mark S. Cragg
Claire Harris
Clare L. Scott
Reviews03 Apr 2009
Nature Reviews Cancer

Volume: 9, P: 321-326
Targeting triple-negative breast cancers with the Smac-mimetic birinapant

Najoua Lalaoui
Delphine Merino
John Silke
ResearchOpen Access27 Apr 2020
Cell Death & Differentiation

Volume: 27, P: 2768-2780

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