Oxidative stress is the central element contributing to infertility in men with varicocele, to which the testis responds by way of a number of mechanisms, including heat stress. In this comprehensive Review, Agarwal et al. discuss these responses, which have their own implications in exacerbating the underlying oxidative stress and on the subsequent infertility.
- Ashok Agarwal
- Alaa Hamada
- Sandro C. Esteves
