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Showing 1–50 of 58 results

Advanced filters: Author: C Kostic Clear advanced filters

Early life microbial succession in the gut follows common patterns in humans across the globe

Here, the authors perform a global analysis of over 3000 infant gut samples revealing a universal pattern of microbial changes over the first 1.5 years, with declines in Bifidobacterium and increases in Faecalibacterium, providing a standard for early gut development.

Guilherme Fahur Bottino
Kevin S. Bonham
Vanja Klepac-Ceraj
ResearchOpen Access14 Jan 2025
Nature Communications

Volume: 16, P: 1-12
High-Resolution Autoradiography without Loss of Water-soluble Ions

F. J. HASSBROEK
J. C. NOGGLE
A. L. FLEMING
Research11 Aug 1962
Nature

Volume: 195, P: 615-616
Yanomami skin microbiome complexity challenges prevailing concepts of healthy skin

Here, the authors show that the skin microbiome of a remote hunter-gatherer Yanomami community harbors environmental microbes that help maintain skin barrier integrity and combat oxidative stress—functions that are reduced by industrial lifestyles.

Juliana Durack
Yvette Piceno
Rita R. Colwell
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-13
An experimental study on effect of curvatures of upstream tube on thermal performance of downstream tube in cross-flow of air

Kunal
Sushil Kumar Dhiman
ResearchOpen Access26 Apr 2025
Scientific Reports

Volume: 15, P: 1-24
Reconstruction of ancient microbial genomes from the human gut

Ancient microbiomes from palaeofaeces are more similar to non-industrialized than industrialized human gut microbiomes regardless of geography, but 39% of their de novo reconstructed genomes represent previously undescribed microbial species.

Marsha C. Wibowo
Zhen Yang
Aleksandar D. Kostic
ResearchOpen Access12 May 2021
Nature

Volume: 594, P: 234-239
Lysophosphatidic acid enhances survival of human CD34⁺ cells in ischemic conditions

Ivana Kostic
Isabel Fidalgo-Carvalho
Lino Ferreira
ResearchOpen Access10 Nov 2015
Scientific Reports

Volume: 5, P: 1-18
Anti-biofouling adsorptive sheet based on polyethersulfone/ dried algal biomass / ZnO nanoparticles for dyes removal

Doaa Hussein
Ahmed E. Abdelhamid
Ahmed Labena
ResearchOpen Access21 May 2025
Scientific Reports

Volume: 15, P: 1-26
The genomic landscape of Mexican Indigenous populations brings insights into the peopling of the Americas

Indigenous populations, including in those in Mexico are underrepresented in genetic studies. Here, the authors perform a population genetics study of indigenous peoples in Mexico to explore demographic histories of the region in the context of geography and cultural influences.

Humberto García-Ortiz
Francisco Barajas-Olmos
Lorena Orozco
ResearchOpen Access12 Oct 2021
Nature Communications

Volume: 12, P: 1-12
Cancer cells impair monocyte-mediated T cell stimulation to evade immunity

Inflammatory monocytes are identified as important players in T cell restimulation in the tumour microenvironment.

Anais Elewaut
Guillem Estivill
Anna C. Obenauf
ResearchOpen Access27 Nov 2024
Nature

Volume: 637, P: 716-725
The role of the intestinal microbiota in type 1 diabetes mellitus

A growing number of studies have shown changes to gut microbiota in children who go on to develop type 1 diabetes mellitus. This Review discusses the strengths and limitations of existing research, covering animal models of the disease and observational human studies. The technology used to characterize intestinal microbiota and recommendations for future studies are also addressed.

Mikael Knip
Heli Siljander
Reviews04 Jan 2016
Nature Reviews Endocrinology

Volume: 12, P: 154-167
Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer

Julius Gudmundsson
Patrick Sulem
Kari Stefansson
Research10 Feb 2008
Nature Genetics

Volume: 40, P: 281-283
High-resolution bacterial 16S rRNA gene profile meta-analysis and biofilm status reveal common colorectal cancer consortia

Julia L. Drewes
James R. White
Cynthia L. Sears
ResearchOpen Access29 Nov 2017
npj Biofilms and Microbiomes

Volume: 3, P: 1-12
Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement

Allergen-specific immunotherapy is used to treat patients affected by acute immunoglobulin E (IgE) responses, but the function mechanism is unclear. Here the authors show that the administration of two cat allergen-specific IgGs reduces allergic responses in mouse models and helps ameliorate clinical symptoms in a phase 1b clinical trial.

J. M. Orengo
A. R. Radin
G. D. Yancopoulos
ResearchOpen Access12 Apr 2018
Nature Communications

Volume: 9, P: 1-15
Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor–positive breast cancer

Simon N Stacey
Andrei Manolescu
Kari Stefansson
Research27 May 2007
Nature Genetics

Volume: 39, P: 865-869
Common variants on chromosome 5p12 confer susceptibility to estrogen receptor–positive breast cancer

Simon N Stacey
Andrei Manolescu
Kari Stefansson
Research27 Apr 2008
Nature Genetics

Volume: 40, P: 703-706
Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo

The development of Sulfopin, a highly selective and potent, covalent Pin1 inhibitor that phenocopies Pin1 knockout and regresses tumors in murine and zebrafish models of neuroblastoma as well as in a pancreatic cancer mouse model.

Christian Dubiella
Benika J. Pinch
Nir London
Research10 May 2021
Nature Chemical Biology

Volume: 17, P: 954-963
Identification of a potent and selective covalent Pin1 inhibitor

A highly selective covalent peptide inhibitor of the peptidyl-prolyl cis/trans isomerase NIMA-interacting 1 (Pin1) is used to show that Pin1 cooperates with mutant KRAS to promote pancreatic ductal adenocarcinoma (PDAC) transformation.

Benika J. Pinch
Zainab M. Doctor
Nathanael S. Gray
Research01 Jun 2020
Nature Chemical Biology

Volume: 16, P: 979-987
Identification and functional analysis of novel THAP1 mutations

Katja Lohmann
Nils Uflacker
Norbert Brüggemann
Research17 Aug 2011
European Journal of Human Genetics

Volume: 20, P: 171-175
New data on spermiogenesis and trepaxonematan axoneme in basal tapeworms (Cestoda, Caryophyllidea, Lytocestidae) parasitizing cyprinid fishes

Martina Matoušková
Tomáš Bílý
Jana Nebesářová
ResearchOpen Access09 Sept 2019
Scientific Reports

Volume: 9, P: 1-11
Discovery of a selective inhibitor of doublecortin like kinase 1

A highly selective inhibitor of the DCLK1/2 kinases is used to uncover the consequences of DCLK1 inhibition on viability, phosphosignaling and the transcriptome in patient-derived organoid models of pancreatic ductal adenocarcinoma.

Fleur M. Ferguson
Behnam Nabet
Nathanael S. Gray
Research06 Apr 2020
Nature Chemical Biology

Volume: 16, P: 635-643
A microbiome-dependent gut–brain pathway regulates motivation for exercise

It is demonstrated that the brain circuitry involved in regulating the motivation for physical activity is not strictly central nervous system autonomous but is shaped by peripheral influences that originate in the intestinal microbial community.

Lenka Dohnalová
Patrick Lundgren
Christoph A. Thaiss
Research14 Dec 2022
Nature

Volume: 612, P: 739-747
Meta-omics analysis of elite athletes identifies a performance-enhancing microbe that functions via lactate metabolism

A closer look at the gut microbiome of elite marathon runners unveils a microbe-encoded enzymatic process that contributes to enhanced athletic performance.

Jonathan Scheiman
Jacob M. Luber
Aleksandar D. Kostic
Research24 Jun 2019
Nature Medicine

Volume: 25, P: 1104-1109
A gut microbial signature for combination immune checkpoint blockade across cancer types

Efforts to identify microbial signatures of response to immune checkpoint blockade suggest that strain-level associations may be cancer type agnostic but cancer therapy specific.

Ashray Gunjur
Yan Shao
Trevor D. Lawley
ResearchOpen Access01 Mar 2024
Nature Medicine

Volume: 30, P: 797-809
Brain-based classification of youth with anxiety disorders: transdiagnostic examinations within the ENIGMA-Anxiety database using machine learning

The study performed on a large, heterogeneous and multisite sample of youth with anxiety disorders reveals that only modest classification performances can be realistically achieved with machine learning using neuroanatomical data.

Willem B. Bruin
Paul Zhutovsky
Moji Aghajani
Research10 Jan 2024
Nature Mental Health

Volume: 2, P: 104-118
Local force and geometry sensing regulate cell functions

Cycles of mechanosensing, mechanotransduction and mechanoresponse regulate cell behaviour and other important cellular responses, such as growth, differentiation and cell death. Nanofabrication and other new technologies have enabled systematic analysis of the mechanisms of mechanosensing and the downstream cellular responses.

Viola Vogel
Michael Sheetz
Reviews22 Feb 2006
Nature Reviews Molecular Cell Biology

Volume: 7, P: 265-275
My diabetes care: an AI-based mobile app with conversational agent for type 2 diabetes self-management

T. Ummal Sariba Begum
R. Renuga Devi
Bosko Nikolic
ResearchOpen Access17 Nov 2025
Scientific Reports

Volume: 15, P: 1-18
Lentiviral vector-mediated gene transfer in adult mouse photoreceptors is impaired by the presence of a physical barrier

O Grüter
C Kostic
Y Arsenijevic
Research17 Mar 2005
Gene Therapy

Volume: 12, P: 942-947
Contributions of the microbial hydrogen economy to colonic homeostasis

Colonic gases are integral to digestion, with changes in the volume and composition of these gases linked to bowel disorders. In this Review, the authors provide a comprehensive discussion of the clinical importance of colonic gases in health and disease, describing the microbes involved in production and utilization of these gases and the types of gastrointestinal diseases linked to them.

Franck Carbonero
Ann C. Benefiel
H. Rex Gaskins
Reviews15 May 2012
Nature Reviews Gastroenterology & Hepatology

Volume: 9, P: 504-518
Microbial shifts and signatures of long-term remission in ulcerative colitis after faecal microbiota transplantation

Susana Fuentes
Noortje G Rossen
Cyriel Y Ponsioen
Research11 Apr 2017
The ISME Journal

Volume: 11, P: 1877-1889
The BRAINTEASER Datasets: Clinical, Wearable and Environmental Data for ALS & MS Progression Modeling

Guglielmo Faggioli
Laura Menotti
Nicola Ferro
ResearchOpen Access21 Nov 2025
Scientific Data

Volume: 12, P: 1-15
The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke

Anna Helgadottir
Andrei Manolescu
Kari Stefansson
Research08 Feb 2004
Nature Genetics

Volume: 36, P: 233-239
Toll-like receptor 3 promotes cross-priming to virus-infected cells

Oliver Schulz
Sandra S. Diebold
Caetano Reis e Sousa
Research13 Feb 2005
Nature

Volume: 433, P: 887-892
Plasma carotenoids as biomarkers of intake of fruits and vegetables: ecological-level correlations in the European Prospective Investigation into Cancer and Nutrition (EPIC)

W K Al-Delaimy
N Slimani
E Riboli
Research14 Sept 2005
European Journal of Clinical Nutrition

Volume: 59, P: 1397-1408
Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

Solveig Gretarsdottir, Kari Stefansson and colleagues report a genome-wide association study for abdominal aortic aneurysm. They identified a variant located within the DAB2IP gene on 9q33 associated with risk of developing abdominal aortic aneurysm.

Solveig Gretarsdottir
Annette F Baas
Kari Stefansson
Research11 Jul 2010
Nature Genetics

Volume: 42, P: 692-697
Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24

Julius Gudmundsson
Patrick Sulem
Kari Stefansson
Research01 Apr 2007
Nature Genetics

Volume: 39, P: 631-637
Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice

Christer Betsholtz, Christine Klein, Maria Sobrido and colleagues report the identification of mutations in the gene encoding PDGF-B that cause idiopathic basal ganglia calcification. They also show that mice carrying hypomorphic Pdgfb alleles develop brain calcifications.

Annika Keller
Ana Westenberger
Joao R M Oliveira
Research04 Aug 2013
Nature Genetics

Volume: 45, P: 1077-1082
A common variant associated with prostate cancer in European and African populations

Laufey T Amundadottir
Patrick Sulem
Kari Stefansson
Research07 May 2006
Nature Genetics

Volume: 38, P: 652-658
A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer

Thorunn Rafnar and colleagues identify a variant on 4p16.3 near FGFR3 associated with increased risk of urinary bladder cancer. They find that the risk allele is more frequent among individuals with tumors that carry an activating somatic mutation in FGFR3, suggesting a link between germline variation, somatic mutation status and cancer risk.

Lambertus A Kiemeney
Patrick Sulem
Kari Stefansson
Research28 Mar 2010
Nature Genetics

Volume: 42, P: 415-419
Gross morphology and adhesion-associated physical properties of Drosophila larval salivary gland glue secretion

Milan Beňo
Denisa Beňová-Liszeková
Robert Farkaš
ResearchOpen Access29 Apr 2024
Scientific Reports

Volume: 14, P: 1-27
PHACTR1 genetic variability is not critical in small vessel ischemic disease patients and PcomA recruitment in C57BL/6J mice

Clemens Messerschmidt
Marco Foddis
Celeste Sassi
ResearchOpen Access16 Mar 2021
Scientific Reports

Volume: 11, P: 1-11
Activity analysis of housekeeping promoters using self-inactivating lentiviral vector delivery into the mouse retina

C Kostic
F Chiodini
Y Arsenijevic
Research17 Apr 2003
Gene Therapy

Volume: 10, P: 818-821
Modernization, collectivism, and gender equality predict love experiences in 45 countries

Piotr Sorokowski
Marta Kowal
Agnieszka Sorokowska
ResearchOpen Access14 Jan 2023
Scientific Reports

Volume: 13, P: 1-10
The myeloid immune signature of enterotoxigenic Bacteroides fragilis-induced murine colon tumorigenesis

E Thiele Orberg
H Fan
F Housseau
Research15 Jun 2016
Mucosal Immunology

Volume: 10, P: 421-433
Interleukin-15 promotes intestinal dysbiosis with butyrate deficiency associated with increased susceptibility to colitis

Marlies Meisel
Toufic Mayassi
Dionysios A Antonopoulos
Research20 Sept 2016
The ISME Journal

Volume: 11, P: 15-30
The HLA-DQβ1 insertion is a strong achalasia risk factor and displays a geospatial north–south gradient among Europeans

Jessica Becker
Stephan L Haas
Johannes Schumacher
Research06 Jan 2016
European Journal of Human Genetics

Volume: 24, P: 1228-1231
Love and affectionate touch toward romantic partners all over the world

Agnieszka Sorokowska
Marta Kowal
Ilona Croy
ResearchOpen Access04 Apr 2023
Scientific Reports

Volume: 13, P: 1-13
Cortical and subcortical brain structure in generalized anxiety disorder: findings from 28 research sites in the ENIGMA-Anxiety Working Group

Anita Harrewijn
Elise M. Cardinale
Daniel S. Pine
ResearchOpen Access01 Oct 2021
Translational Psychiatry

Volume: 11, P: 1-15
Relationship between the morphology of the foveal avascular zone, retinal structure, and macular circulation in patients with diabetes mellitus

Nathan M. Bates
Jing Tian
Delia Cabrera DeBuc
ResearchOpen Access29 Mar 2018
Scientific Reports

Volume: 8, P: 1-12
Whole-genome re-sequencing of non-model organisms: lessons from unmapped reads

A Gouin
F Legeai
C Lemaitre
Research01 Oct 2014
Heredity

Volume: 114, P: 494-501
Components of variation in serum carotenoid concentrations: the Polyp Prevention Trial

M R Forman
C B Borkowf
E Lanza
Research16 Apr 2008
European Journal of Clinical Nutrition

Volume: 63, P: 763-770

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