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Showing 51–100 of 659 results

Advanced filters: Author: C Smit Clear advanced filters

TEIPP-vaccination in checkpoint-resistant non-small cell lung cancer: a first-in-human phase I/II dose-escalation study

Tumor cells can evade immune detection by downregulating commonly recognized antigens, presenting a major challenge for effective immunotherapy. In this first-in-human study, the authors showed that the activation of T cells recognizing a new class of tumor antigens presented by immunotherapy-escaped tumor cells is safe and may lead to clinical benefit.

Mitchell Emmers
Marij J. P. Welters
Sjoerd H. van der Burg
ResearchOpen Access28 May 2025
Nature Communications

Volume: 16, P: 1-14
Single-cell long-read sequencing-based mapping reveals specialized splicing patterns in developing and adult mouse and human brain

RNA alternative splicing is involved in determining cell identity, but a comprehensive molecular map is missing. Here, the authors provide a human and mouse brain atlas of transcript isoforms linking them to cellular identity, brain regions and development stages.

Anoushka Joglekar
Wen Hu
Hagen U. Tilgner
ResearchOpen Access09 Apr 2024
Nature Neuroscience

Volume: 27, P: 1051-1063
Genome-wide analysis of the interplay between chromatin-associated RNA and 3D genome organization in human cells

How chromatin-associated RNAs (caRNAs) are spatially organized in the context of the multiscale genome architecture is unclear. Here the authors suggest how the 3D genome architecture can modulate the spatial distribution of caRNAs at different scales, and how in turn caRNA could affect the dynamic 3D genome organization.

Riccardo Calandrelli
Xingzhao Wen
Sheng Zhong
ResearchOpen Access16 Oct 2023
Nature Communications

Volume: 14, P: 1-14
Initial sequencing and comparative analysis of the mouse genome

Asif T. Chinwalla
Lisa L. Cook
Michael C. Zody
Research05 Dec 2002
Nature

Volume: 420, P: 520-562
Upper Cretaceous to Eocene pelagic limestones of the Scaglia Rossa are not Miocene turbidites

Walter Alvarez
William Lowrie
Research19 Nov 1981
Nature

Volume: 294, P: 246-248
Genetic loci influencing kidney function and chronic kidney disease

John Chambers and colleagues identify common variants at four loci associated with serum creatinine levels, a marker of kidney function. Their findings provide insight into the pathways underlying susceptibility to chronic kidney disease.

John C Chambers
Weihua Zhang
Jaspal S Kooner
Research11 Apr 2010
Nature Genetics

Volume: 42, P: 373-375
A saturated map of common genetic variants associated with human height

A large genome-wide association study of more than 5 million individuals reveals that 12,111 single-nucleotide polymorphisms account for nearly all the heritability of height attributable to common genetic variants.

Loïc Yengo
Sailaja Vedantam
Joel N. Hirschhorn
ResearchOpen Access12 Oct 2022
Nature

Volume: 610, P: 704-712
Targeting the latent human cytomegalovirus reservoir for T-cell-mediated killing with virus-specific nanobodies

Human cytomegalovirus (HCMV) can evade immune responses in latent reservoirs, which is a specific problem during transplantation. Here the authors develop a bivalent nanobody that is specific for US28, a viral receptor required by latent HCMV, and show it can partially reactivate the virus and make it susceptible to killing by T cells.

Timo W. M. De Groof
Elizabeth G. Elder
Martine J. Smit
ResearchOpen Access21 Jul 2021
Nature Communications

Volume: 12, P: 1-11
Feasibility of overnight electrical stimulation-induced muscle activation in people with a spinal cord injury. A Pilot study

Christof A. J. Smit
Frank Berenpas
Thomas W. J. Janssen
Research24 Jan 2020
Spinal Cord Series and Cases

Volume: 6, P: 1-8
Electrophysiological resting-state signatures link polygenic scores to general intelligence

Rebecca Engler
Christina Stammen
Erhan Genç
ResearchOpen Access21 Nov 2025
Scientific Reports

Volume: 15, P: 1-20
Determination of the Radial Velocity of a Relativistic Star

A. C. LE FLOCH
Research23 May 1970
Nature

Volume: 226, P: 737-738
The first cubane-type fluoro-bridged cluster

J. C. JANSEN
H. VAN KONINGSVELD
J. REEDIJK
Research01 Sept 1977
Nature

Volume: 269, P: 318-319
Effects of Pressure on some Optical and Electrical Properties of Diamonds

F. C. CHAMPION
J. R. PRIOR
Research18 Oct 1958
Nature

Volume: 182, P: 1079-1080
Accelerated cisplatin and high-dose epirubicin with G-CSF support in patients with relapsed non-small-cell lung cancer: feasibility and efficacy

C Huisman
B Biesma
E F Smit
ResearchOpen Access13 Nov 2001
British Journal of Cancer

Volume: 85, P: 1456-1461
A unique geochemical record at the Permian/Triassic boundary

William T. Holser
Hans-Peter Schönlaub
Rupert Schmöller
Research05 Jan 1989
Nature

Volume: 337, P: 39-44
Vitamins in Rose Hips

FRANK WOKES
E. H. JOHNSON
F. C. JACOBY
Research06 Mar 1943
Nature

Volume: 151, P: 279
Reticulocyte Enzymes and Protein Synthesis

DRUMMOND ELLIS
C. ELIZABETH SEWELL
L. G. SKINNER
Research28 Jan 1956
Nature

Volume: 177, P: 190-191
Does C₆₀ have a liquid phase?

M. H. J. Hagen
E. J. Meijer
H. N. W. Lekkerkerker
Research30 Sept 1993
Nature

Volume: 365, P: 425-426
Vernalization of Lettuce

A. C. SIMPSON
Research06 Mar 1943
Nature

Volume: 151, P: 279-280
Single-haplotype comparative genomics provides insights into lineage-specific structural variation during cat evolution

Single-haplotype genome assemblies from five cat species shed light on the dynamics of structural variations during felid radiation and resolve sensory gene repertoires associated with adaptation and domestication.

Kevin R. Bredemeyer
LaDeana Hillier
William J. Murphy
Research02 Nov 2023
Nature Genetics

Volume: 55, P: 1953-1963
Transposon-activated POU5F1B promotes colorectal cancer growth and metastasis

The treatment of colorectal cancer (CRC) is an unmet medical need in absence of early diagnosis. Here, the authors characterise cancer-specific transposable element-driven transpochimeric gene transcripts and highlight the role of POU5F1B in CRC growth and metastasis.

Laia Simó-Riudalbas
Sandra Offner
Didier Trono
ResearchOpen Access20 Aug 2022
Nature Communications

Volume: 13, P: 1-17
Stimulation of Phagocytosis in Relation to the Mechanism of Action of Adjuvants

T. NICOL
D. C. QUANTOCK
B. VERNON-ROBERTS
Research12 Mar 1966
Nature

Volume: 209, P: 1142-1143
Shisa6 traps AMPA receptors at postsynaptic sites and prevents their desensitization during synaptic activity

Auxiliary AMPA receptor subunits can affect gating and surface mobility. Here the authors show that Shisa6 traps AMPA receptors at postsynaptic sites via PSD-95, and keeps them in an activated state in the presence of glutamate, preventing full desensitization and consequently synaptic depression.

Remco V. Klaassen
Jasper Stroeder
August B. Smit
ResearchOpen Access02 Mar 2016
Nature Communications

Volume: 7, P: 1-12
Evolution of DNA methylome from precancerous lesions to invasive lung adenocarcinomas

It is known that invasive lung adenocarcinomas evolve from pre-cancerous dysplastic lesions. In this study, the authors show that evolution of pre-cancerous lesions is accompanied by DNA methylation alterations, and that global hypomethylation correlates with immune infiltration, mutational burden and copy number alterations.

Xin Hu
Marcos R. Estecio
Jianjun Zhang
ResearchOpen Access29 Jan 2021
Nature Communications

Volume: 12, P: 1-13
The induction of tumour immunity in mice using glutaraldehyde-treated tumour cells

C. J. SANDERSON
P. FROST
Research19 Apr 1974
Nature

Volume: 248, P: 690-691
Adaptive reduction in permeability of avian eggshells to water vapour at high altitudes

GARY C. PACKARD
PAUL R. SOTHERLAND
MARY J. PACKARD
Research01 Mar 1977
Nature

Volume: 266, P: 255-256
Evidence for β-Oxidation in the Metabolism of Saturated Aliphatic Hydrocarbons by Soil Species of Nocardia

D. M. WEBLEY
R. B. DUFF
V. C. FARMER
Research29 Dec 1956
Nature

Volume: 178, P: 1467-1468
New Broad Spectrum Anthelmintic, Methyl 5(6)-Butyl-2-benzimidazolecarbamate

P. ACTOR
E. L. ANDERSON
V. J. THEODORIDES
Research15 Jul 1967
Nature

Volume: 215, P: 321-322
Isolation of a Sex Hormone from the Water Mould Achlya bisexualis

T. C. MCMORRIS
ALMA W. BARKSDALE
Research15 Jul 1967
Nature

Volume: 215, P: 320-321
Mechanism for Fluorine Inhibition of Diffusion in Hydroxyapatite

R. A. YOUNG
W. VAN DER LUGT
J. C. ELLIOTT
Research16 Aug 1969
Nature

Volume: 223, P: 729-730
Mercury-Selenium Correlations in Marine Mammals

J. H. KOEMAN
W. H. M. PEETERS
J. J. M. DE GOEIJ
Research19 Oct 1973
Nature

Volume: 245, P: 385-386
Indoleacetaldehydes: Serotonin-like Effects on the Central Nervous System

H. C. SABELLI
W. J. GIARDINA
F. UNGAR
Research05 Jul 1969
Nature

Volume: 223, P: 73-74
Ion Exchange Method of estimating Strontium-90 and Other Radionuclides in Rainwater

C. BRENAN
J. H. LOVATT
H. SMITH
Research02 Jul 1966
Nature

Volume: 211, P: 68-69
Effect of Solar Radiation on the Harvester Termite, Hodotermes mossambicus (Hagen)

J. J. C. NEL
P. H. HEWITT
Research23 Aug 1969
Nature

Volume: 223, P: 862-863
Post-Exposure Analysis of Organic Compounds in the Blood by a Rapid Infra-Red Technique

R. D. STEWART
D. S. ERLEY
C. L. HAKE
Research18 Jul 1959
Nature

Volume: 184, P: 192-193
Reversal by Diethyl-Stilbœstrol of the Depressant Effect of Cortisone on the Phagocytic Activity of the Reticulo-endothelial System

T. NICOL
D. L. J. BILBEY
Research01 Jun 1957
Nature

Volume: 179, P: 1137-1138
Optical fibres in an Antarctic sponge

R. Cattaneo-Vietti
G. Bavestrello
E. Gaino
Research03 Oct 1996
Nature

Volume: 383, P: 397-398
Immuno-adsorbents of High Capacity

J. C. METCALFE
H. F. MARLOW
A. S. V. BURGEN
Research12 Mar 1966
Nature

Volume: 209, P: 1142
Ionic Distribution deduced from the g-Factor of a Ferrimagnetic Spinel: Ti⁴⁺ in Fourfold Co-ordination

E. W. GORTER
Research16 Jan 1954
Nature

Volume: 173, P: 123-124
Antigenic Property of the Oral Secretion of Fleas

E. BENJAMINI
BEN F. FEINGOLD
L. KARTMAN
Research10 Dec 1960
Nature

Volume: 188, P: 959-960
Induced molecule self-organization

PHILIP C. H. MITCHELL
Research11 Jul 1991
Nature

Volume: 352, P: 116
The Precambrian-Cambrian boundary and geochemical perturbations

KENNETH J. HSÜ
Research20 Feb 1986
Nature

Volume: 319, P: 697
Protein Synthesis in Nucleated and Non-nucleated Halves of Acetabularia mediterranea studied with Carbon-14 Dioxide

J. BRACHET
H. CHANTRENNE
Research01 Dec 1951
Nature

Volume: 168, P: 950
scFvs get down to basics: How MuSK makes synapses

Bruce Wallace
Research01 Aug 1997
Nature Biotechnology

Volume: 15, P: 721-722
The Skipper (Scomberesox saurus) in the Southern North Sea and the Thames Estuary

ALWYNE C. WHEELER
M. N. MISTAKIDIS
Research22 Oct 1960
Nature

Volume: 188, P: 334-335
Decomposition of Ferrosic Sulphide to Pyrrhotite in an Electron Microscope

MASAYUKI UDA
Research02 Jul 1966
Nature

Volume: 211, P: 67-68
Orienting Power of the Nitroso-Group and the Formula of Nitrosobenzene

R. J. W. LE FÈVRE
Research10 Sept 1932
Nature

Volume: 130, P: 400-401
Observations of waves and plasma in the environment of comet Halley

R. Grard
A. Pedersen
V. Formisano
Research15 May 1986
Nature

Volume: 321, P: 290-291
Association between plausible genetic factors and weight loss from GLP1-RA and bariatric surgery

The authors found, after analyzing 10,960 individuals from 9 multiancestry biobanks across 6 countries, that genetic factors previously associated with BMI have limited impact on GLP-1 receptor agonist-induced weight loss.

Jakob German
Mattia Cordioli
Andrea Ganna
ResearchOpen Access18 Apr 2025
Nature Medicine

Volume: 31, P: 2269-2276
Long-term isolation of European steppe outposts boosts the biome’s conservation value

Europe hosts isolated remnants of the steppe belt that once covered much of Eurasia. Here the authors combine genomic data and ecological niche modelling on three plant and three insect species to show evolution independent of the zonal steppe and high conservation value of these extrazonal steppes.

Philipp Kirschner
Eliška Záveská
Peter Schönswetter
ResearchOpen Access23 Apr 2020
Nature Communications

Volume: 11, P: 1-10

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