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Showing 1–2 of 2 results
Advanced filters: Author: Cai-Tao Li Clear advanced filters
  • mRNA modifications like m5C are typically introduced by tRNA-modifying enzymes, while the catalytic mechanism and function remain debated. Here, the authors show that NSUN6 catalyzes tRNA and mRNA substrates in different ways, and that NSUN6 promotes breast cancer cell migration through mRNA m5C modification.

    • Yuan-Yuan Zhang
    • Cai-Tao Li
    • Ru-Juan Liu
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-19
  • tRNA-derived small RNAs (tdRs) have long been considered mere intermediates of tRNA degradation. This Review discusses the biogenesis and regulation of tdRs and focuses on their emerging gene regulation roles in cell metabolism, immune responses, development and cancer.

    • Sowndarya Muthukumar
    • Cai-Tao Li
    • Cristian Bellodi
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 25, P: 359-378