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Showing 1–4 of 4 results
Advanced filters: Author: Cara M. Altimus Clear advanced filters

  • The mammalian retina has three types of light-sensing cells: rods, cones and melanopsin-containing cells. Rods and cones are involved in vision but have also been shown to contribute to light-entrainment of the circadian clock. Rods and cones must signal through melanopsin-containing cells for the latter.

    • Ali D. Güler
    • Jennifer L. Ecker
    • Samer Hattar
    Research
    Nature
    Volume: 453, P: 102-105

  • The intrinsically photosensitive melanopsin-expressing retinal ganglion neurons are important for nonvisual responses to light, such as circadian photoentrainment. These cells, however, require high light intensities to be activated and it has been unclear how photoentrainment to low light levels works. This study finds that rod photoreceptors are essential to photoentrainment at low and middle light intensities.

    • Cara M Altimus
    • Ali D Güler
    • Samer Hattar
    Research
    Nature Neuroscience
    Volume: 13, P: 1107-1112