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Showing 1–2 of 2 results
Advanced filters: Author: Cecile Dalban Clear advanced filters

  • A clinical cohort-based biomarker study in patients with metastatic renal cell carcinoma demonstrates that blood levels of soluble mucosal addressin cell adhesion molecule-1 are prognostic for survival in patients treated with tyrosine kinase inhibitors and immune checkpoint inhibitors and may serve as a surrogate marker for gut dysbiosis based on integrated data from three clinical trials.

    • Carolina Alves Costa Silva
    • Marc Machaalani
    • Laurence Albiges
    ResearchOpen Access
    Nature Medicine
    P: 1-11

  • We describe netrin-1 upregulation in a majority of human endometrial carcinomas and demonstrate that netrin-1 blockade, using the anti-netrin-1 antibody NP137, is effective both in a mouse model and in patients with endometrial carcinomas.

    • Philippe A. Cassier
    • Raul Navaridas
    • Patrick Mehlen
    ResearchOpen Access
    Nature
    Volume: 620, P: 409-416