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Nature Communications (2)
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Showing 1–4 of 4 results

Advanced filters: Author: Changhe Huang Clear advanced filters

Calcium-sensitive synaptotagmin 11-lipid interaction modulates exo-endocytosis

Syt1 is a primary Ca²⁺ sensor for secretion but the function of non-Ca²⁺ -affinitive Syt11 remains unknown. Here, authors identify strong but Ca²⁺ -inhibited lipid affinity of Syt11, and a Syt11-1-11 inter-switch during excitation-coupled exo-endocytosis.

Xuanang Wu
Jingyu Yao
Huadong Xu
ResearchOpen Access16 Dec 2025
Nature Communications

Volume: 17, P: 1-16
Synaptotagmin-11 is a critical mediator of parkin-linked neurotoxicity and Parkinson’s disease-like pathology

Mutations in the parkin, an ubiquitin ligase, are linked to Parkinson’s disease. Here the authors show that synaptotagmin-11 is a parkin substrate and that its upregulation affects dopamine release, triggers degeneration, and causes motor impairment.

Changhe Wang
Xinjiang Kang
Zhuan Zhou
ResearchOpen Access08 Jan 2018
Nature Communications

Volume: 9, P: 1-14
Prediction of the corrosion rates of subsea pipelines via KPCA

Shiqi Xu
Changhe Huang
Hongda Zhao
ResearchOpen Access08 Jul 2025
Scientific Reports

Volume: 15, P: 1-14
Prevalence and factors associated with hepatitis C among pregnant women in China: a cross-sectional study

Sun He
Gao Shuang
Wang Qian
ResearchOpen Access14 Jan 2023
Scientific Reports

Volume: 13, P: 1-8