Huang et al. investigate serum metabolomic profiles from aging cohorts in Taiwan and Japan to identify biomarkers of physio-cognitive decline syndrome. They report significant alterations in glutathione, tryptophan, and bile acid pathways, with metabolites including creatinine and 3-hydroxykynurenine as potential indicators.
- Yi-Long Huang
- Wei-Ju Chang
- Liang-Kung Chen
