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Showing 1–4 of 4 results
Advanced filters: Author: Chaogu Zheng Clear advanced filters

  • C. elegans has lost DNA methylation and the methyl-binding domain in MBD-2 reader. The authors show that Cel-MBD-2 is a conserved NuRD component. Cel-MBD-2 can either localize to open chromatin with NuRD, or to repressive histone marks without NuRD.

    • Hok Ning Tsui
    • Charmaine Yan Yu Wong
    • Karen Wing Yee Yuen
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-23

  • Non-destructive methods to image metabolism in situ in living tissues are limited. Here the authors combine deuterium oxide probing and stimulated Raman scattering microscopy to image lipid metabolic dynamics and protein synthesis in cells and in vivo in mice, C. elegans, and zebrafish.

    • Lingyan Shi
    • Chaogu Zheng
    • Wei Min
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-17

  • Small vibrational tags (azide, 13C-edited carbonyl and deuterium-labeled probes) were introduced as metabolic probes for mid-infrared imaging. The tags allow unprecedented in situ visualization of metabolism in cells and animals with high information throughput.

    • Lixue Shi
    • Xinwen Liu
    • Wei Min
    Research
    Nature Methods
    Volume: 17, P: 844-851