Elevated serum uric acid levels before 20 weeks of gestation are associated with the development of preeclampsia, especially in the early 8–12 weeks of gestation, and the effect attenuates with increasing gestational weeks, which suggest that elevated uric acid in early pregnancy may be a causative factor in preeclampsia.
- Chaoyan Yue
- Chunmei Ying
- Xiaotian Li