Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–8 of 8 results
Advanced filters: Author: Charles F. Delisle Clear advanced filters

  • Absorption lines of iron in the dayside atmosphere of an ultrahot giant exoplanet disappear after travelling across the nightside, showing that the iron has condensed during its travel.

    • David Ehrenreich
    • Christophe Lovis
    • Filippo Zerbi
    Research
    Nature
    Volume: 580, P: 597-601

  • Locally elevated cholesterol in colorectal cancer cells with adenomatous polyposis coli truncation was observed to drive Wnt–β-catenin signaling through Dishevelled (Dvl). Inhibitors targeting the cholesterol–Dvl interaction potently suppress tumor growth without adverse side effects.

    • Ashutosh Sharma
    • Julian Zalejski
    • Wonhwa Cho
    Research
    Nature Chemical Biology
    Volume: 21, P: 1376-1386

  • From 1980 to 2018, the levels of total and non-high-density lipoprotein cholesterol increased in low- and middle-income countries, especially in east and southeast Asia, and decreased in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe.

    • Cristina Taddei
    • Bin Zhou
    • Majid Ezzati
    ResearchOpen Access
    Nature
    Volume: 582, P: 73-77

  • The vascular, cellular and molecular changes underlying sex differences in mood disorders are unclear. Here, the authors show that blood-brain barrier dysfunction modulates anxiety- and depressive-like behaviors in female mice and endothelium-specific changes associated with maladaptive responses compared to resilience to stress.

    • Laurence Dion-Albert
    • Alice Cadoret
    • Caroline Menard
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-18

  • Intrinsically disordered proteins are frequently dysregulated in many diseases, but because of their heterogeneous, highly dynamic structural states they have been considered largely ‘undruggable’ by traditional approaches. This Review proposes that a synergy of advanced experimental and computational approaches will help to overcome this barrier to drug discovery.

    • Tamas Lazar
    • Acadia Connor
    • Peter Tompa
    Reviews
    Nature Reviews Drug Discovery
    Volume: 24, P: 743-763