Nature Search

c-Src phosphorylation and activation of hexokinase promotes tumorigenesis and metastasis

The protein tyrosine kinase c-Src is a renowned proto-oncogene with pleiotropic effects. Here, the authors show that c-Src induces the metabolic reprogramming of cancer cells by phosphorylating hexokinases HK1 and HK2, which in turns lead to increased HK catalytic activity and consequent enhancement of glycolysis.

Jia Zhang
Suili Wang
Qinxi Li
ResearchOpen Access05 Jan 2017
Nature Communications

Volume: 8, P: 1-16
Curcumin attenuates the progression of hemorrhoids through the inhibition of angiogenesis via miR-190a-5p/TGFBR2

Heng Zhang
Chunling Li
Xu Han
ResearchOpen Access23 Jan 2026
Scientific Reports

Volume: 16, P: 1-13
Protomelission is an early dasyclad alga and not a Cambrian bryozoan

Protomelission-like macrofossils from the Xiaoshiba Lagerstätte show features characteristic of dasycladalean green alga, suggesting that Protomelission is unlikely to be an early bryozoan.

Jie Yang
Tian Lan
Martin R. Smith
Research08 Mar 2023
Nature

Volume: 615, P: 468-471
Nf2-FAK signaling axis is critical for cranial bone ossification and regeneration

Nf2 physically engages with focal adhesion kinase (FAK) to preferentially mediate Erk1/2 and PI3K catalytic p110 subunit/Akt signaling, regulating osteogenic lineage development, cranial bone ossification and regeneration.

Junguang Liao
Yuping Huang
Guiqian Chen
ResearchOpen Access12 Mar 2025
Nature Communications

Volume: 16, P: 1-17
A brain somatic RHEB doublet mutation causes focal cortical dysplasia type II

Shanshan Zhao
Zhenghui Li
Yun-wu Zhang
ResearchOpen Access23 Jul 2019
Experimental & Molecular Medicine

Volume: 51, P: 1-11
Immunoglobulin M perception by FcμR

The structural basis for the molecular mechanism of recognition of different IgM forms by the IgM receptor FcμR is determined using crystallography and cryo-electron microscopy.

Yaxin Li
Hao Shen
Junyu Xiao
Research22 Mar 2023
Nature

Volume: 615, P: 907-912
Morphological and genetic evidence for early Holocene cattle management in northeastern China

The domestication of cattle took place during the early Holocene, independently in the Near East and in southern Asia. Here, Zhang et al.provide evidence for management of taurine cattle in northern China, an area not previously considered as an independent domestication centre.

Hucai Zhang
Johanna L.A. Paijmans
Michael Hofreiter
Research08 Nov 2013
Nature Communications

Volume: 4, P: 1-7
Altered microbiota of the lower respiratory tract and its association with COVID-19 severity analysed by metagenomics and metatranscriptomics

Mechanistic modeling of enhancer-RNA sheds light on the role of transcription factors and their interactions in the context of estrogen-induced transcriptional program in breast cancer.

Denian Wang
Yishang Duan
Weimin Li
ResearchOpen Access26 May 2025
Communications Biology

Volume: 8, P: 1-12
Haplotype-resolved T2T genome assembly of the Populus nigra NL-1976

Fenfen Liu
Chenggong Liu
Qinjun Huang
ResearchOpen Access09 Dec 2025
Scientific Data

Volume: 13, P: 1-12
GCN5-targeted dual-modal probe across the blood-brain barrier for borders display in invasive glioblastoma

The development of imaging agents capable of clearly defining tumor margins is essential for GBM intraoperative navigation. Here this group identifies GCN5 as a promising molecular target for GBM imaging therefore designs a dual mode nanoprobe for BBB crossing and in vivo visualization of typical GBM tumor boundaries.

Haiyan Zheng
Lu Zhang
Tianhai Ji
ResearchOpen Access08 Mar 2025
Nature Communications

Volume: 16, P: 1-17
Organ systems of a Cambrian euarthropod larva

Youti yuanshi is a euarthropod species newly described from a fossilized larva from Yunnan Province, China dating approximately to late Atdabanian stage, Cambrian period, and provides insights into the evolution of arthropods.

Martin R. Smith
Emma J. Long
Xiguang Zhang
ResearchOpen Access31 Jul 2024
Nature

Volume: 633, P: 120-126
Decoupled responses of plants and soil biota to global change across the world’s land ecosystems

Understanding how global changes affect both aboveground plants and belowground soil organisms is essential for preserving ecosystem functions and biodiversity. This study synthesizes extensive data, revealing decoupled responses in plant and soil biota to global changes across different biomes.

Qingshui Yu
Chenqi He
Jingyun Fang
ResearchOpen Access29 Nov 2024
Nature Communications

Volume: 15, P: 1-12
Benchmarking AI-powered docking methods from the perspective of virtual screening

Artificial intelligence (AI)-based docking and scoring methods demonstrate considerable potential for virtual drug screening. Gu et al. go further by assessing the structural rationality of AI-predicted complex conformations from various sources.

Shukai Gu
Chao Shen
Yu Kang
Research13 Feb 2025
Nature Machine Intelligence

Volume: 7, P: 509-520
LRRC75A-AS1 facilitates breast cancer cell proliferation and invasion via functioning as a CeRNA to modulate miR489-3p/ARD1

Chunjiao Yu
Zhiyuan Wang
Shan Yan
ResearchOpen Access26 Aug 2025
Scientific Reports

Volume: 15, P: 1-13
Differences in Clinicopathology of Early Gastric Carcinoma between Proximal and Distal Location in 438 Chinese Patients

Qin Huang
Cheng Fang
Hiroshi Mashimo
ResearchOpen Access27 Aug 2015
Scientific Reports

Volume: 5, P: 1-12
Identifying long-term stable refugia for relict plant species in East Asia

East Asia contains “relict” plant species that persist under narrow climatic conditions after once having wider distributions. Here, using distribution records coupled with ecological niche models, the authors identify long-term stable refugia possessing past, current and future climatic suitability favoring ancient plant lineages.

Cindy Q. Tang
Tetsuya Matsui
Jordi López-Pujol
ResearchOpen Access26 Oct 2018
Nature Communications

Volume: 9, P: 1-14
Restoration of X-ray phase-contrast imaging based on generative adversarial networks

Jiacheng Zeng
Jianheng Huang
Chenggong Zhang
ResearchOpen Access31 Oct 2024
Scientific Reports

Volume: 14, P: 1-14
Allogenic and autologous anti-CD7 CAR-T cell therapies in relapsed or refractory T-cell malignancies

Yinqiang Zhang
Chenggong Li
Heng Mei
ResearchOpen Access25 Apr 2023
Blood Cancer Journal

Volume: 13, P: 1-10
A Two stage deep learning network for automated femoral segmentation in bilateral lower limb CT scans

Wenqing Xie
Peng Chen
Da Zhong
ResearchOpen Access17 Mar 2025
Scientific Reports

Volume: 15, P: 1-13
Author Correction: Identifying long-term stable refugia for relict plant species in East Asia

Cindy Q. Tang
Tetsuya Matsui
Jordi López-Pujol
Amendments and CorrectionsOpen Access04 Dec 2018
Nature Communications

Volume: 9, P: 1-2
Evidence for lunar tide effects in Earth’s plasmasphere

Lunar tides affect Earth’s oceans and its geomagnetic field. Multisatellite observations demonstrate that they also impact the plasmasphere.

Chao Xiao
Fei He
Zhao Zhang
ResearchOpen Access26 Jan 2023
Nature Physics

Volume: 19, P: 486-491
Bispecific CS1-BCMA CAR-T cells are clinically active in relapsed or refractory multiple myeloma

Chenggong Li
Jia Xu
Heng Mei
ResearchOpen Access17 Oct 2023
Leukemia

Volume: 38, P: 149-159
Integrated in vitro, in silico, and in vivo approaches to elucidate the antidiabetic mechanisms of Cicer arietinum and Hordeum vulgare extract and secondary metabolites

Asif Shahzad
Wenjing Liu
Zhe Yang
ResearchOpen Access24 Feb 2025
Scientific Reports

Volume: 15, P: 1-26
Calciphytoliths (calcium oxalate crystals) analysis for the identification of decayed tea plants (Camellia sinensis L.)

Jianping Zhang
Houyuan Lu
Linpei Huang
ResearchOpen Access24 Oct 2014
Scientific Reports

Volume: 4, P: 1-9
Prognosis of HIV Patients Receiving Antiretroviral Therapy According to CD4 Counts: A Long-term Follow-up study in Yunnan, China

Li Ren
Juan Li
Kunhua Wang
ResearchOpen Access29 Aug 2017
Scientific Reports

Volume: 7, P: 1-7
Nitrogen addition restricts key soil ecological enzymes and nutrients by reducing microbial abundance and diversity

Xiaodong Li
Lianbo Su
Yali Song
ResearchOpen Access14 Feb 2025
Scientific Reports

Volume: 15, P: 1-16
A genomic instability-associated lncRNA signature for predicting prognosis and biomarkers in lung adenocarcinoma

Chunxuan Lin
Kunpeng Lin
Chenggong Wei
ResearchOpen Access24 Jun 2024
Scientific Reports

Volume: 14, P: 1-13
Using ML techniques to predict extubation outcomes for patients with central nervous system injuries in the Yun-Gui Plateau

Zi-han Chen
Hao-tian Wu
Xue Yang
ResearchOpen Access22 May 2025
Scientific Reports

Volume: 15, P: 1-13
High-fidelity DNA histograms in neoplastic progression in Barrett's esophagus

Chenggong Yu
Xiaoqi Zhang
Raj K Goyal
Research19 Feb 2007
Laboratory Investigation

Volume: 87, P: 466-472
Hybrid sequencing for detailed genetic characterization of human adenoviruses

Bin Fang
Juan Lai
Xin Zhang
ResearchOpen Access27 Nov 2024
Scientific Reports

Volume: 14, P: 1-13
Tumour-derived small extracellular vesicles contribute to the tumour progression through reshaping the systemic immune macroenvironment

Zhimin Du
Hui Zhang
Jinheng Wang
Research08 Feb 2023
British Journal of Cancer

Volume: 128, P: 1249-1266
Design and evaluation of a solar powered smart irrigation system for sustainable urban agriculture

Mahmoud A. Abdelhamid
Tarek Kh. Abdelkader
Mohamed F. Atia
ResearchOpen Access06 Apr 2025
Scientific Reports

Volume: 15, P: 1-20
ADCK1 activates the β-catenin/TCF signaling pathway to promote the growth and migration of colon cancer cells

Yong Ji
Yiqian Liu
Yufeng Huang
ResearchOpen Access06 Apr 2021
Cell Death & Disease

Volume: 12, P: 1-12
Tissue remodeling after ocular surface reconstruction with denuded amniotic membrane

Jing Jie
Jie Yang
Wei Li
ResearchOpen Access23 Apr 2018
Scientific Reports

Volume: 8, P: 1-11
New sedimentary evidence reveals a unique history of C₄ biomass in continental East Asia since the early Miocene

Bin Zhou
Michael Bird
David Taylor
ResearchOpen Access13 Mar 2017
Scientific Reports

Volume: 7, P: 1-9
NCAPH plays important roles in human colon cancer

Liang Yin
Li-Ping Jiang
Yong-Bin Chen
ResearchOpen Access16 Mar 2017
Cell Death & Disease

Volume: 8, P: e2680

Search

c-Src phosphorylation and activation of hexokinase promotes tumorigenesis and metastasis

Curcumin attenuates the progression of hemorrhoids through the inhibition of angiogenesis via miR-190a-5p/TGFBR2

Protomelission is an early dasyclad alga and not a Cambrian bryozoan

Nf2-FAK signaling axis is critical for cranial bone ossification and regeneration

A brain somatic RHEB doublet mutation causes focal cortical dysplasia type II

Immunoglobulin M perception by FcμR

Morphological and genetic evidence for early Holocene cattle management in northeastern China

Altered microbiota of the lower respiratory tract and its association with COVID-19 severity analysed by metagenomics and metatranscriptomics

Haplotype-resolved T2T genome assembly of the Populus nigra NL-1976

GCN5-targeted dual-modal probe across the blood-brain barrier for borders display in invasive glioblastoma

Organ systems of a Cambrian euarthropod larva

Decoupled responses of plants and soil biota to global change across the world’s land ecosystems

Benchmarking AI-powered docking methods from the perspective of virtual screening

LRRC75A-AS1 facilitates breast cancer cell proliferation and invasion via functioning as a CeRNA to modulate miR489-3p/ARD1

Differences in Clinicopathology of Early Gastric Carcinoma between Proximal and Distal Location in 438 Chinese Patients

Identifying long-term stable refugia for relict plant species in East Asia

Restoration of X-ray phase-contrast imaging based on generative adversarial networks

Allogenic and autologous anti-CD7 CAR-T cell therapies in relapsed or refractory T-cell malignancies

A Two stage deep learning network for automated femoral segmentation in bilateral lower limb CT scans

Author Correction: Identifying long-term stable refugia for relict plant species in East Asia

Evidence for lunar tide effects in Earth’s plasmasphere

Bispecific CS1-BCMA CAR-T cells are clinically active in relapsed or refractory multiple myeloma

Integrated in vitro, in silico, and in vivo approaches to elucidate the antidiabetic mechanisms of Cicer arietinum and Hordeum vulgare extract and secondary metabolites

Calciphytoliths (calcium oxalate crystals) analysis for the identification of decayed tea plants (Camellia sinensis L.)

Prognosis of HIV Patients Receiving Antiretroviral Therapy According to CD4 Counts: A Long-term Follow-up study in Yunnan, China

Nitrogen addition restricts key soil ecological enzymes and nutrients by reducing microbial abundance and diversity

A genomic instability-associated lncRNA signature for predicting prognosis and biomarkers in lung adenocarcinoma

Using ML techniques to predict extubation outcomes for patients with central nervous system injuries in the Yun-Gui Plateau

High-fidelity DNA histograms in neoplastic progression in Barrett's esophagus

Hybrid sequencing for detailed genetic characterization of human adenoviruses

Tumour-derived small extracellular vesicles contribute to the tumour progression through reshaping the systemic immune macroenvironment

Design and evaluation of a solar powered smart irrigation system for sustainable urban agriculture

ADCK1 activates the β-catenin/TCF signaling pathway to promote the growth and migration of colon cancer cells

Tissue remodeling after ocular surface reconstruction with denuded amniotic membrane

New sedimentary evidence reveals a unique history of C₄ biomass in continental East Asia since the early Miocene

NCAPH plays important roles in human colon cancer

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