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Communications Biology (1)

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ATPase N-ethylmaleimide-sensitive factor mediated calcium dependent fusion pore closure and endocytosis

N-ethylmaleimide-sensitive factor (NSF) mediated disassembly of trans-SNARE complexes is identified as the mechanism regulating fusion pore closure. This activity is critical for Ca²⁺dependent exo-endocytosis coupling and vesicle pool maintenance.

Yudong Wang
Siyang Ma
Dongsheng Wang
ResearchOpen Access26 Feb 2026
Communications Biology

P: 1-13

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ATPase N-ethylmaleimide-sensitive factor mediated calcium dependent fusion pore closure and endocytosis

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