Nature Search

Protective humoral and cellular immune responses to SARS-CoV-2 persist up to 1 year after recovery

The quality of immune response to SARS-CoV-2 is thought to wane over time, but it is unclear how long it can persist. Here the authors show persistent immune responses in a large number of patients over the course of a 1-year follow-up from the time of recovery from COVID-19.

Chengqian Feng
Jingrong Shi
Feng Li
ResearchOpen Access17 Aug 2021
Nature Communications

Volume: 12, P: 1-7
Atomic-level Cu active sites enable energy-efficient CO₂ electroreduction to multicarbon products in strong acid

Tandem electrocatalysts are developed for acidic CO₂ electroreduction. The catalyst contains planar-copper for CO₂ reduction to CO, and a dual-copper-active-site layer for CO reduction to C₂₊ products. An ethanol Faradaic efficiency of 46% and a C₂₊ Faradaic efficiency of 91% are achieved in acidic electrolyte at 150 mA cm⁻².

Lizhou Fan
Feng Li
Edward Sargent
Research26 Nov 2024
Nature Synthesis

Volume: 4, P: 262-270
Interferon stimulated immune profile changes in a humanized mouse model of HBV infection

There is increasing evidence that treatment of hepatitis B with interferon alpha can be beneficial. Here, Wang et al, present a type 1 interferon receptor humanized mouse model and characterize it as a platform in which to study interferon function in vivo.

Yaping Wang
Liliangzi Guo
Feng Li
ResearchOpen Access15 Nov 2023
Nature Communications

Volume: 14, P: 1-16
The protective role of DOT1L in UV-induced melanomagenesis

The interaction of DOT1L with MLL oncogenic fusion proteins has been implicated in leukemogenesis. Here, the authors show a contrasting role for DOT1L in protecting UVR-induced melanomagenesis by facilitating DNA repair through interaction with XPC.

Bo Zhu
Shuyang Chen
Rutao Cui
ResearchOpen Access17 Jan 2018
Nature Communications

Volume: 9, P: 1-13
Somatically hypermutated antibodies isolated from SARS-CoV-2 Delta infected patients cross-neutralize heterologous variants

In this study, authors identified neutralizing antibodies by isolating B cells from SARS-CoV-2 Delta infected patients and detect altered structural features, likely introduced by somatic hypermutation, that are involved in epitope binding and increase neutralization breadth against virus variants.

Haisheng Yu
Banghui Liu
Xiaoping Tang
ResearchOpen Access24 Feb 2023
Nature Communications

Volume: 14, P: 1-14
A novel anti-loosening bolt looseness diagnosis of bolt connections using a vision-based technique

Jun Luo
Kaili Li
Yuanlai Wang
ResearchOpen Access20 May 2024
Scientific Reports

Volume: 14, P: 1-14
Shared gene signatures and molecular mechanisms link ankylosing spondylitis and rheumatoid arthritis

Boli Qin
Xiaopeng Qin
Chong Liu
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-15
Hierarchically oriented organization in supramolecular peptide crystals

Hierarchical self-assembly and crystallization is ubiquitous in nature and is of key importance for creation of complex superstructures. Herein, Yuan and co-workers propose that hierarchically oriented organization guides the formation of such complex systems, especially in supramolecular peptide crystals.

Chengqian Yuan
Wei Ji
Xuehai Yan
Reviews10 Sept 2019
Nature Reviews Chemistry

Volume: 3, P: 567-588
Investigating ferroptosis-related genes NFE2L2 in neutrophils for ankylosing spondylitis: therapeutic potential of cassia twigs

Tianyou Chen
Jichong Zhu
Chong Liu
ResearchOpen Access10 Mar 2025
Scientific Reports

Volume: 15, P: 1-15
Sequential introduction of reprogramming factors reveals a time-sensitive requirement for individual factors and a sequential EMT–MET mechanism for optimal reprogramming

Pei and colleagues show that introduction of the pluripotency reprogramming factors in sequence (Oct4–Klf4, c-Myc and finally Sox-2), rather than introducing them all together, increases reprogramming efficiency. This sequential delivery activates the epithelial-to-mesenchymal transition (EMT) before the mesenchymal-to-epithelial transition (MET), which was previously reported to occur during reprogramming. The authors also show that addition of EMT modulators influences reprogramming in a similar manner.

Xiaopeng Liu
Hao Sun
Hui Zheng
Research26 May 2013
Nature Cell Biology

Volume: 15, P: 829-838
The shared role of neutrophils in ankylosing spondylitis and ulcerative colitis

Tianyou Chen
Weiming Tan
Chong Liu
Research25 Jul 2024
Genes & Immunity

Volume: 25, P: 324-335
Stoichiometry-controlled secondary structure transition of amyloid-derived supramolecular dipeptide co-assemblies

Bipyridine derivatives have been shown to control the self-assembly of amyloid-derived dipeptides. Here the authors show that 4,4'-bipyridine inhibits the formation of amyloid-like beta-sheet assembly by Fmoc-protected diphenylalanine, prompting a reorganisation to helical structure, and characterise the transition pathway.

Wei Ji
Chengqian Yuan
Ehud Gazit
ResearchOpen Access13 Jun 2019
Communications Chemistry

Volume: 2, P: 1-11
Prediction model for spinal cord injury in spinal tuberculosis patients using multiple machine learning algorithms: a multicentric study

Sitan Feng
Shujiang Wang
Xinli Zhan
ResearchOpen Access02 Apr 2024
Scientific Reports

Volume: 14, P: 1-11
Lysine-specific histone demethylase 1 inhibition promotes reprogramming by facilitating the expression of exogenous transcriptional factors and metabolic switch

Hao Sun
Lining Liang
Hui Zheng
ResearchOpen Access02 Aug 2016
Scientific Reports

Volume: 6, P: 1-14
Sequential EMT-MET induces neuronal conversion through Sox2

Songwei He
Jinlong Chen
Hui Zheng
ResearchOpen Access30 May 2017
Cell Discovery

Volume: 3, P: 1-14

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