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DISC1 Protects Against Zika Virus Infection and Long-Term Neurological Damage Through AMPK-mTOR-Mediated Autophagy

DISC1 attenuates Zika virus infection and congenital Zika syndrome by promoting autophagy via AMPK-mTOR signaling and is implicated in ZIKV-induced long-term neurological deficits.

Shengze Zhang
Haolu Zha
Huanle Luo
ResearchOpen Access07 Nov 2025
Nature Communications

Volume: 16, P: 1-20
Heat-stable protein PGSL1 enhances pollen germination and tube growth at high temperature

The actin cytoskeleton plays crucial roles in pollen development, germination, and tube growth. Here the authors show that PGSL1, an Arabidopsis heat-stable actin binding protein stabilizes actin filaments under high temperatures, preventing denaturation and maintaining F-actin dynamics.

Dong Qian
Tian Li
Yun Xiang
ResearchOpen Access17 Apr 2025
Nature Communications

Volume: 16, P: 1-17
Structural and functional insights into the tetrameric photosystem I from heterocyst-forming cyanobacteria

The 2.37 Å structure of a tetrameric photosystem I complex from the cyanobacterium Anabaena shows a dimer of dimers organization. This oligomerization is physiologically linked to cyclic electron flow and thylakoid membrane organization.

Lvqin Zheng
Yanbing Li
Ning Gao
Research08 Oct 2019
Nature Plants

Volume: 5, P: 1087-1097
Structural snapshot of cytoplasmic pre-60S ribosomal particles bound by Nmd3, Lsg1, Tif6 and Reh1

The cryo-EM structure of pre-60S purified via Nmd3 provides molecular insights into the roles of assembly factors Nmd3, Lsg1, Tif6 and Reh1 in the last steps of ribosomal large-subunit maturation.

Chengying Ma
Shan Wu
Ning Gao
Research23 Jan 2017
Nature Structural & Molecular Biology

Volume: 24, P: 214-220
VSIG4 inhibits proinflammatory macrophage activation by reprogramming mitochondrial pyruvate metabolism

Macrophage differentiation and inflammatory function are controlled by cell metabolism. Here, the authors use a viral hepatitis model and a high-fat diet model of insulin resistance to show how VSIG4 inhibits inflammatory macrophage activation by modulating mitochondrial pyruvate metabolism.

Jialin Li
Bo Diao
Yuzhang Wu
ResearchOpen Access06 Nov 2017
Nature Communications

Volume: 8, P: 1-14
Non-Hermitian topological whispering gallery

An acoustic topological gallery insulator constructed from sonic crystals made of thermoplastic rods decorated with carbon nanotube films enables the out-coupling of amplified and focused sound at audible frequencies.

Bolun Hu
Zhiwang Zhang
Johan Christensen
Research29 Sept 2021
Nature

Volume: 597, P: 655-659
Theory of non-Hermitian topological whispering gallery

René Pernas-Salomón
Li-Yang Zheng
Johan Christensen
ResearchOpen Access18 Nov 2022
npj Computational Materials

Volume: 8, P: 1-7
The tea plant reference genome and improved gene annotation using long-read and paired-end sequencing data

Enhua Xia
Fangdong Li
Xiaochun Wan
ResearchOpen Access15 Jul 2019
Scientific Data

Volume: 6, P: 1-9

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