DNA repeats can lengthen or shorten during their replication, which may lead to a human disease. Here, the authors discovered that an essential replication protein, Mcm10, counteracts instability of GAA repeats, implicated in Friedreich’s ataxia, as well as death of repeat-containing cells.
- Chiara Masnovo
- Zohar Paleiov
- Sergei M. Mirkin
