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Lower vaccine-acquired immunity in the elderly population following two-dose BNT162b2 vaccination is alleviated by a third vaccine dose

Responses to SARS-CoV-2 vaccines in different populations are important to define efficacy. Here the authors show using a cohort in Singapore that two doses of mRNA vaccine is less effective in recipients over 60 years of age and that a further dose of vaccine can improve these antibody levels.

Laurent Renia
Yun Shan Goh
Lisa F. P. Ng
ResearchOpen Access08 Aug 2022
Nature Communications

Volume: 13, P: 1-16
Higher Delta variant-specific neutralizing antibodies prevented infection in close contacts vaccinated with ancestral mRNA vaccines during the SARS-CoV-2 Delta wave

Yun Shan Goh
Siew-Wai Fong
Laurent Renia
ResearchOpen Access07 Nov 2023
Scientific Reports

Volume: 13, P: 1-7
Resistance of SARS-CoV-2 variants to neutralization by convalescent plasma from early COVID-19 outbreak in Singapore

Bei Wang
Yun Shan Goh
Cheng-I Wang
ResearchOpen Access25 Oct 2021
npj Vaccines

Volume: 6, P: 1-9
Bystander CD8⁺ T cells are abundant and phenotypically distinct in human tumour infiltrates

Human lung and colorectal tumours contain a population of tumour-infiltrating lymphocytes that are specific for tumour-unrelated antigens and, unlike tumour-antigen-specific tumour-infiltrating lymphocytes, do not express CD39.

Yannick Simoni
Etienne Becht
Evan W. Newell
Research16 May 2018
Nature

Volume: 557, P: 575-579
Author Correction: Higher Delta variant-specific neutralizing antibodies prevented infection in close contacts vaccinated with ancestral mRNA vaccines during the SARS-CoV-2 Delta wave

Yun Shan Goh
Siew-Wai Fong
Laurent Renia
Amendments and CorrectionsOpen Access17 Jan 2024
Scientific Reports

Volume: 14, P: 1-2
Engineering immunosuppressive drug-resistant armored (IDRA) SARS-CoV-2 T cells for cell therapy

Qi Chen
Adeline Chia
Antonio Bertoletti
Research05 Sept 2023
Cellular & Molecular Immunology

Volume: 20, P: 1300-1312
Employment of a high throughput functional assay to define the critical factors that influence vaccine induced cross-variant neutralizing antibodies for SARS-CoV-2

Yue Gu
Bhuvaneshwari Shunmuganathan
Paul A. MacAry
ResearchOpen Access09 Dec 2023
Scientific Reports

Volume: 13, P: 1-14

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Lower vaccine-acquired immunity in the elderly population following two-dose BNT162b2 vaccination is alleviated by a third vaccine dose

Higher Delta variant-specific neutralizing antibodies prevented infection in close contacts vaccinated with ancestral mRNA vaccines during the SARS-CoV-2 Delta wave

Resistance of SARS-CoV-2 variants to neutralization by convalescent plasma from early COVID-19 outbreak in Singapore

Bystander CD8+ T cells are abundant and phenotypically distinct in human tumour infiltrates

Author Correction: Higher Delta variant-specific neutralizing antibodies prevented infection in close contacts vaccinated with ancestral mRNA vaccines during the SARS-CoV-2 Delta wave

Engineering immunosuppressive drug-resistant armored (IDRA) SARS-CoV-2 T cells for cell therapy

Employment of a high throughput functional assay to define the critical factors that influence vaccine induced cross-variant neutralizing antibodies for SARS-CoV-2

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Bystander CD8⁺ T cells are abundant and phenotypically distinct in human tumour infiltrates