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Showing 1–3 of 3 results
Advanced filters: Author: Christopher DiPasquale Clear advanced filters

  • Siles Alvarado and Schuler et al. examine the long-term dynamics of SARS-CoV-2 antibodies in individuals with varying COVID-19 severities over 12 months. While anti-N antibodies decline, anti-RBD antibodies persist, offering insights into the evolving immunity post-COVID.

    • Nadia Siles Alvarado
    • Maisey Schuler
    • Esther Melamed
    ResearchOpen Access
    Communications Medicine
    Volume: 5, P: 1-13

  • A reactivity-based probe containing an iron-sensitive 1,2,4-trixolane ring conjugated to a small molecule payload combined with a high-throughput immunofluorescence assay enables the selective detection of labile intracellular ferrous iron.

    • Benjamin Spangler
    • Charles W Morgan
    • Adam R Renslo
    Research
    Nature Chemical Biology
    Volume: 12, P: 680-685

  • Polyoxygenated aliphatic chains with multiple hydroxyl groups are common in a wide array of compounds, often with potent biological activity. Now, a new ruthenium catalyst enables selective dehydrogenation of a single hydroxyl group in a broad scope of complex polyols. This site-selective modification facilitates the rapid incorporation of nitrogen-based functional groups into diverse natural products.

    • Christopher K. Hill
    • John F. Hartwig
    Research
    Nature Chemistry
    Volume: 9, P: 1213-1221