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Showing 1–16 of 16 results
Advanced filters: Author: Christopher E. Skelton Clear advanced filters

  • BamA carries out the essential process of folding outer membrane β-barrels in Gram-negative bacteria and is a potential antibiotic target. Here, the authors discover macrocyclic peptide inhibitors that trap BamA in distinct structural conformations.

    • Dawei Sun
    • Kelly M. Storek
    • Jian Payandeh
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-15

  • Weak perturbations couple solitons—nonlinear pulses—to low-amplitude linear waves. Longstanding mathematical results indicate that this phenomenon is universal. The authors verify these predictions experimentally by demonstrating that the coupling amplitude satisfies a general scaling law.

    • Justin Widjaja
    • Y. Long Qiang
    • C. Martijn de Sterke
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-8

  • Chronic infection with SARS-CoV-2 leads to the emergence of viral variants that show reduced susceptibility to neutralizing antibodies in an immunosuppressed individual treated with convalescent plasma.

    • Steven A. Kemp
    • Dami A. Collier
    • Ravindra K. Gupta
    Research
    Nature
    Volume: 592, P: 277-282

  • Sera from vaccinated individuals and some monoclonal antibodies show a modest reduction in neutralizing activity against the B.1.1.7 variant of SARS-CoV-2; but the E484K substitution leads to a considerable loss of neutralizing activity.

    • Dami A. Collier
    • Anna De Marco
    • Ravindra K. Gupta
    Research
    Nature
    Volume: 593, P: 136-141

  • A study of the evolution of the SARS-CoV-2 virus in England between September 2020 and June 2021 finds that interventions capable of containing previous variants were insufficient to stop the more transmissible Alpha and Delta variants.

    • Harald S. Vöhringer
    • Theo Sanderson
    • Moritz Gerstung
    ResearchOpen Access
    Nature
    Volume: 600, P: 506-511

  • The Vertebrate Genome Project has used an optimized pipeline to generate high-quality genome assemblies for sixteen species (representing all major vertebrate classes), which have led to new biological insights.

    • Arang Rhie
    • Shane A. McCarthy
    • Erich D. Jarvis
    ResearchOpen Access
    Nature
    Volume: 592, P: 737-746

  • Safely opening university campuses has been a major challenge during the COVID-19 pandemic. Here, the authors describe a program of public health measures employed at a university in the United States which, combined with other non-pharmaceutical interventions, allowed the university to stay open in fall 2020 with limited evidence of transmission.

    • Diana Rose E. Ranoa
    • Robin L. Holland
    • Martin D. Burke
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-16

  • Gutekunst et al. explore the phylogeographic origins of the marbled crayfish, Procambarus virginalis, a parthenogenetic freshwater species. Based on genomic data of the parent species, they demonstrate that both parental haplotypes of P. virginalis were inherited from the Everglades subpopulation of P. fallax.

    • Julian Gutekunst
    • Olena Maiakovska
    • Frank Lyko
    ResearchOpen Access
    Communications Biology
    Volume: 4, P: 1-6

  • FlyWire presents a neuronal wiring diagram of the whole fly brain with annotations for cell types, classes, nerves, hemilineages and predicted neurotransmitters, with data products and an open ecosystem to facilitate exploration and browsing.

    • Sven Dorkenwald
    • Arie Matsliah
    • Meet Zandawala
    ResearchOpen Access
    Nature
    Volume: 634, P: 124-138

  • Researchers from Hawaii and an international consortium have produced a draft genome assembly for 'SunUp', the first commercial virus-resistant transgenic fruit tree. Comparison of this plant genome to those of Arabidopsis and others sheds light on evolution of characteristics such as biosynthesis, starch deposition, control of photosynthesis and pathways for creating volatile compounds.

    • Ray Ming
    • Shaobin Hou
    • Maqsudul Alam
    ResearchOpen Access
    Nature
    Volume: 452, P: 991-996