Nature Search

Predicting fault slip via transfer learning

By teaching machine learning models with earthquake fault numerical simulations laboratory fault slip is predictable. Training the model further with a snippet of laboratory data improves predictions suggesting an approach to probing faults in Earth.

Kun Wang
Christopher W. Johnson
Paul A. Johnson
ResearchOpen Access16 Dec 2021
Nature Communications

Volume: 12, P: 1-11
Author Correction: SARS-CoV-2 evolution during treatment of chronic infection

Steven A. Kemp
Dami A. Collier
Ravindra K. Gupta
Amendments and Corrections21 Jul 2022
Nature

Volume: 608, P: E23
Cognitive behavioral therapy for antiretroviral therapy adherence and treatment outcomes among people living with HIV: a systematic review and meta-analysis

Cognitive behavioral therapy (CBT) is increasingly recognized for its potential to improve antiretroviral therapy adherence among people living with HIV. Here the authors conduct a systematic review and meta-analysis, revealing that CBT significantly enhances adherence, especially in individuals with psychiatric comorbidities and in low- and middle-income countries, although effects on viral metrics remain unclear.

David R. A. Coelho
Belinda J. Njiro
Alex S. Keuroghlian
Research10 Jun 2025
Nature Mental Health

Volume: 3, P: 735-746
1156 POLYOL PATHWAY HYPERKINESIS IN CHILDREN WITH DIABETES

John I Malone
Gail F Knox
Christopher Harvey
Research01 Apr 1981
Pediatric Research

Volume: 15, P: 635
Functional materials discovery using energy–structure–function maps

Energy–structure–function maps that describe the possible structures and properties of molecular crystals are developed, and these maps are used to guide the experimental discovery of porous materials with specific functions.

Angeles Pulido
Linjiang Chen
Graeme M. Day
Research22 Mar 2017
Nature

Volume: 543, P: 657-664
African-American men with low-risk prostate cancer treated with radical prostatectomy in an equal-access health care system: implications for active surveillance

Rishi Deka
J. Kellogg Parsons
Brent S. Rose
Research23 Apr 2020
Prostate Cancer and Prostatic Diseases

Volume: 23, P: 581-588
Performance of clinicopathologic models in men with high risk localized prostate cancer: impact of a 22-gene genomic classifier

Jeffrey J. Tosoian
Samuel R. Birer
Daniel E. Spratt
Research30 Mar 2020
Prostate Cancer and Prostatic Diseases

Volume: 23, P: 646-653
The intraprostatic immune environment after stereotactic body radiotherapy is dominated by myeloid cells

Nicholas G. Nickols
Ekambaram Ganapathy
Dörthe Schaue
Research09 Jul 2020
Prostate Cancer and Prostatic Diseases

Volume: 24, P: 135-139
Testosterone therapy does not increase the risks of prostate cancer recurrence or death after definitive treatment for localized disease

Reith R. Sarkar
Sunil H. Patel
Brent S. Rose
Research08 Jun 2020
Prostate Cancer and Prostatic Diseases

Volume: 23, P: 689-695
Trans-complex formation by proteolipid channels in the terminal phase of membrane fusion

Christopher Peters
Martin J. Bayer
Andreas Mayer
Research01 Feb 2001
Nature

Volume: 409, P: 581-588
A germ-free humanized mouse model shows the contribution of resident microbiota to human-specific pathogen infection

Resident microbiota contribute to HIV and EBV infection in a germ-free humanized mouse model.

Angela Wahl
Wenbo Yao
J. Victor Garcia
Research10 Aug 2023
Nature Biotechnology

Volume: 42, P: 905-915
A Family History of Lethal Prostate Cancer and Risk of Aggressive Prostate Cancer in Patients Undergoing Radical Prostatectomy

Omer A. Raheem
Seth A. Cohen
Christopher J. Kane
ResearchOpen Access26 Jun 2015
Scientific Reports

Volume: 5, P: 1-6
Machine learning for diagnosis of myocardial infarction using cardiac troponin concentrations

A clinical decision support system for diagnosis of myocardial infarction, based on machine learning models that use a single measurement of high-sensitivity troponin, outperforms clinical guidelines that use fixed cardiac troponin thresholds for diagnosis.

Dimitrios Doudesis
Kuan Ken Lee
Stephen W. Smith
ResearchOpen Access11 May 2023
Nature Medicine

Volume: 29, P: 1201-1210
Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy

In a multicenter research program coordinated by the International Mouse Phenotyping Consortium, Spielmann et al. analyze the cardiac function and structure in ~4,000 monogenic mutant mice and identify 705 mouse genes involved in cardiac function, 75% of which have not been previously linked to cardiac heritable disease in humans. Using the UK Biobank human data, the authors validate the link between cardiovascular disease and some of the newly identified genes to illustrate the resource value and potential of their mutant mouse collection.

Nadine Spielmann
Gregor Miller
Martin Hrabe de Angelis
ResearchOpen Access17 Feb 2022
Nature Cardiovascular Research

Volume: 1, P: 157-173
Author Correction: Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Dami A. Collier
Anna De Marco
Ravindra K. Gupta
Amendments and Corrections21 Jul 2022
Nature

Volume: 608, P: E24
Paths and timings of the peopling of Polynesia inferred from genomic networks

Analysis of genomic networks from 430 modern individuals across 21 Pacific island populations reveals the human settlement history of Polynesia.

Alexander G. Ioannidis
Javier Blanco-Portillo
Andrés Moreno-Estrada
Research22 Sept 2021
Nature

Volume: 597, P: 522-526
Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

A randomized trial in patients hospitalized with COVID-19 showed no benefit and potentially increased harm associated with the use of convalescent plasma, with subgroup analyses suggesting that the antibody profile in donor plasma is critical in determining clinical outcomes.

Philippe Bégin
Jeannie Callum
Donald M. Arnold
ResearchOpen Access09 Sept 2021
Nature Medicine

Volume: 27, P: 2012-2024
Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7, encoding a heat-shock protein

DNA sequencing of 3,864 individuals with ALS and 7,839 controls identified a novel disease gene, DNAJC7, which encodes a heat-shock protein. As DNAJC7 is an essential part of cell maintenance, mutations in DNAJC7 may lead to neurodegeneration.

Sali M. K. Farhan
Daniel P. Howrigan
Benjamin M. Neale
Research25 Nov 2019
Nature Neuroscience

Volume: 22, P: 1966-1974
Human and mouse essentiality screens as a resource for disease gene discovery

Discovery of causal variants for monogenic disorders has been facilitated by whole exome and genome sequencing, but does not provide a diagnosis for all patients. Here, the authors propose a Full Spectrum of Intolerance to Loss-of-Function (FUSIL) categorization that integrates gene essentiality information to aid disease gene discovery.

Pilar Cacheiro
Violeta Muñoz-Fuentes
Coleen Kane
ResearchOpen Access31 Jan 2020
Nature Communications

Volume: 11, P: 1-16
Mapping and characterization of structural variation in 17,795 human genomes

Structural variants in more than 17,000 human genomes are mapped and characterized using whole-genome sequencing, showing how this type of variation contributes to rare deleterious coding and noncoding alleles.

Haley J. Abel
David E. Larson
Ira M. Hall
Research27 May 2020
Nature

Volume: 583, P: 83-89
The diagnosis and treatment of early psoriatic arthritis

Psoriatic arthritis follows a chronic, progressive course in most patients and joint damage can occur early in the disease. This article discusses advances in early diagnosis of this inflammatory musculoskeletal disorder, the various therapies that are available, as well as general guiding principles for treatment.

Allen P. Anandarajah
Christopher T. Ritchlin
Reviews06 Oct 2009
Nature Reviews Rheumatology

Volume: 5, P: 634-641
Effects of Repeated Nicotine Administration and Footshock Stress on Rat Mesoprefrontal Dopamine Systems: Evidence for Opioid Mechanisms

Tony P George
Christopher D Verrico
Robert H Roth
Research01 Jul 2000
Neuropsychopharmacology

Volume: 23, P: 79-88
Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility

Classical Hodgkin lymphoma is a cancer that originates in lymph nodes. Little is known about its genetic susceptibility. Here, the authors combined existing and new genome-wide association studies to identify risk loci for classical Hodgkin lymphoma at 6q22.33, and nodular sclerosis Hodgkin lymphoma at 3q28, 6q23.3, 10p14, 13q34, 16p13.13.

Amit Sud
Hauke Thomsen
Richard S. Houlston
ResearchOpen Access01 Dec 2017
Nature Communications

Volume: 8, P: 1-11
Publisher Correction: Genomic reconstruction of the SARS CoV-2 epidemic in England

Harald S. Vöhringer
Theo Sanderson
Moritz Gerstung
Amendments and CorrectionsOpen Access07 Jun 2022
Nature

Volume: 606, P: E18
The sunflower genome provides insights into oil metabolism, flowering and Asterid evolution

A high-quality reference for the sunflower genome (Helianthus annuus L.) and analysis of gene networks involved in flowering time and oil metabolism provide a basis for nutritional exploitation and analyses of adaptation to climate change.

Hélène Badouin
Jérôme Gouzy
Nicolas B. Langlade
ResearchOpen Access22 May 2017
Nature

Volume: 546, P: 148-152
Physiological acclimatization in Hawaiian corals following a 22-month shift in baseline seawater temperature and pH

Rowan H. McLachlan
James T. Price
Andréa G. Grottoli
ResearchOpen Access10 Mar 2022
Scientific Reports

Volume: 12, P: 1-11
Author Correction: Protecting the global ocean for biodiversity, food and climate

Enric Sala
Juan Mayorga
Jane Lubchenco
Amendments and Corrections08 Apr 2021
Nature

Volume: 592, P: E25
KIBRA, MTNR1B, and FKBP5 genotypes are associated with decreased odds of incident delirium in elderly post-surgical patients

Mark Terrelonge
Sara C. LaHue
Vanja C. Douglas
ResearchOpen Access11 Jan 2022
Scientific Reports

Volume: 12, P: 1-6
Select black men are potential candidates for prostate hemi-ablation based on radical prostatectomy histopathology for intermediate-risk prostate cancer—a multicenter SEARCH cohort study

Sriram Deivasigamani
Eric S. Adams
Thomas J. Polascik
Research12 Aug 2024
Prostate Cancer and Prostatic Diseases

Volume: 28, P: 755-760
High-throughput screening assays for the identification of chemical probes

James Inglese
Ronald L Johnson
Douglas S Auld
Reviews18 Jul 2007
Nature Chemical Biology

Volume: 3, P: 466-479
Validity of the National Death Index to ascertain the date and cause of death in men having undergone prostatectomy for prostate cancer

Drew Moghanaki
Lauren E. Howard
Stephen J. Freedland
Research29 Apr 2019
Prostate Cancer and Prostatic Diseases

Volume: 22, P: 633-635
Genome-wide association study identifies multiple susceptibility loci for diffuse large B cell lymphoma

James Cerhan and colleagues report genome-wide association and meta-analysis studies to identify genetic susceptibility loci for diffuse large B cell lymphoma. They identify four loci that influence genetic susceptibility to this B cell malignancy.

James R Cerhan
Sonja I Berndt
Stephen J Chanock
Research28 Sept 2014
Nature Genetics

Volume: 46, P: 1233-1238
IFITM3 restricts the morbidity and mortality associated with influenza

Interferon-inducible transmembrane (IFITM) protein 3 is shown to be an innate defence mechanism against viral infection in vivo; furthermore, a subset of the patients hospitalized during the H1N1 2009 pandemic carried a variant form of the IFITM3 gene.

Aaron R. Everitt
Simon Clare
Paul Kellam
Research25 Mar 2012
Nature

Volume: 484, P: 519-523
Subtle primes of in-group and out-group affiliation change votes in a large scale field experiment

Daniel Rubenson
Christopher T. Dawes
ResearchOpen Access29 Dec 2022
Scientific Reports

Volume: 12, P: 1-10
Separated at birth? The functional and molecular divergence of OLIG1 and OLIG2

Despite their structural similarities and seemingly coordinated expression patterns, oligodendrocyte transcription factor 1 (OLIG1) and OLIG2 have largely non-overlapping roles in CNS development, brain diseases and neural repair. Here, the authors review the molecular factors that may account for the divergent functions of these proteins.

Dimphna H. Meijer
Michael F. Kane
David H. Rowitch
Reviews20 Nov 2012
Nature Reviews Neuroscience

Volume: 13, P: 819-831
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

Richard Trembath and colleagues report a meta-analysis of genome-wide association studies for psoriasis, including 2 cohorts genotyped on the custom Immunochip array, in a total of 10,588 cases and 22,806 controls. They identify 15 new susceptibility loci and refine signals in previously known loci, highlighting a role for innate host defense in susceptibility to psoriasis.

Lam C Tsoi
Sarah L Spain
Richard C Trembath
Research11 Nov 2012
Nature Genetics

Volume: 44, P: 1341-1348
The MR neuroimaging protocol for the Accelerating Medicines Partnership® Schizophrenia Program

Michael P. Harms
Kang-Ik K. Cho
Ofer Pasternak
ResearchOpen Access02 Apr 2025
Schizophrenia

Volume: 11, P: 1-14
Shaping the future of inflammatory bowel disease: a global research agenda for better management and public health response

Inflammatory bowel disease (IBD) is an immune-mediated disease with substantial burden worldwide. In this Consensus Statement, a global multidisciplinary group of experts identify key priorities and recommendations to raise awareness and advance IBD care and research.

Virginia Solitano
Charles N. Bernstein
Silvio Danese
Reviews22 Apr 2025
Nature Reviews Gastroenterology & Hepatology

Volume: 22, P: 438-452
Genomic epidemiology reveals multiple introductions of Zika virus into the United States

Genome sequencing of Zika virus samples from infected patients and Aedes aegypti mosquitoes in Florida shows that the virus was probably introduced into the United States on multiple occasions, and that the Caribbean is the most likely source.

Nathan D. Grubaugh
Jason T. Ladner
Kristian G. Andersen
Research24 May 2017
Nature

Volume: 546, P: 401-405
1219 RESPIRATORY EVALUATION OF CHILDREN IN A CHLORINE GAS DISASTER: IDENTIFICATION OF RISK FACTORS

Judy Palmer
Daniel V Schidlow
Nancy N Huang
Research01 Apr 1978
Pediatric Research

Volume: 12, P: 567
Distinct germline genetic susceptibility profiles identified for common non-Hodgkin lymphoma subtypes

Sonja I. Berndt
Joseph Vijai
Nathaniel Rothman
Research22 Oct 2022
Leukemia

Volume: 36, P: 2835-2844
Hyper- and hypo- nutrition studies of the hepatic transcriptome and epigenome suggest that PPARα regulates anaerobic glycolysis

Anthony R. Soltis
Shmulik Motola
Ernest Fraenkel
ResearchOpen Access14 Mar 2017
Scientific Reports

Volume: 7, P: 1-13
Author Correction: Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility

Amit Sud
Hauke Thomsen
Richard S. Houlston
Amendments and CorrectionsOpen Access08 Jan 2019
Nature Communications

Volume: 10, P: 1-3
Transit detection of the long-period volatile-rich super-Earth ν² Lupi d with CHEOPS

Three planets orbit the Sun-like star ν² Lupi. CHEOPS data show that all of them are transiting and show remarkable diversity. In particular, dry and gas-poor inner planet b has experienced extensive atmospheric loss, while planets c and d are water rich and have a small gaseous envelope of primordial origin.

Laetitia Delrez
David Ehrenreich
Nicholas A. Walton
Research28 Jun 2021
Nature Astronomy

Volume: 5, P: 775-787
Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy

IgA plasmocytes are shown to promote resistance to the immunogenic chemotherapeutic oxaliplatin in prostate cancer mouse models by inhibiting activation of cytotoxic T cells; immunosuppressive plasma cells, which are also found in human-therapy-resistant prostate cancer, are generated in response to TGFβ, and their functionality depends on PD-L1 expression and IL-10 secretion.

Shabnam Shalapour
Joan Font-Burgada
Michael Karin
Research29 Apr 2015
Nature

Volume: 521, P: 94-98
Reply to: Concerns about estimating relative risk of death associated with convalescent plasma for COVID-19

Philippe Bégin
Jeannie Callum
Donald M. Arnold
Research10 Jan 2022
Nature Medicine

Volume: 28, P: 53-58
Publisher Correction: Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy

Nadine Spielmann
Gregor Miller
Martin Hrabe de Angelis
Amendments and CorrectionsOpen Access20 Apr 2022
Nature Cardiovascular Research

Volume: 1, P: 529-531
C. elegans neurons jettison protein aggregates and mitochondria under neurotoxic stress

Adult neurons from Caenorhabditis elegans can extrude large membrane-surrounded vesicles, known as exophers, containing protein aggregates and dysfunctional organelles that threaten neuronal homeostasis.

Ilija Melentijevic
Marton L. Toth
Monica Driscoll
Research08 Feb 2017
Nature

Volume: 542, P: 367-371
African bat database: curated data of occurrences, distributions and conservation metrics for sub-Saharan bats

Ara Monadjem
Cecilia Montauban
Peter J. Taylor
ResearchOpen Access02 Dec 2024
Scientific Data

Volume: 11, P: 1-9
Promoter CpG hypomethylation and transcription factor EGR1 hyperactivate heparanase expression in bladder cancer

Tatsuya Ogishima
Hiroaki Shiina
Rajvir Dahiya
Research20 Jun 2005
Oncogene

Volume: 24, P: 6765-6772

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