Nature Search

Adoptively transferred tumor-specific IL-9-producing cytotoxic CD8⁺ T cells activate host CD4⁺ T cells to control tumors with antigen loss

Xiao et al. report that adoptively transferred tumor-specific CD8⁺ interleukin-9-producing cytotoxic T cells promote the recruitment and activation of host effector CD4⁺ T cells to control the outgrowth of tumors with antigen loss.

Liuling Xiao
Rui Duan
Qing Yi
Research03 Apr 2025
Nature Cancer

Volume: 6, P: 718-735
Realizing four-electron conversion chemistry for all-solid-state Li||I₂ batteries at room temperature

Current Li||I2 batteries suffer from limited capacity and polyiodides shuttling. Here, authors showcase a four-electron all-solid-state Li||I2 battery using a chloride-rich solid electrolyte that enables a solid-phase reversible I^-/I₂/I⁺ conversion, achieving high capacity and enhanced safety.

Zhu Cheng
Hang Liu
Haoshen Zhou
ResearchOpen Access18 Feb 2025
Nature Communications

Volume: 16, P: 1-12
Metformin enhances osteogenic differentiation of BMSC by modulating macrophage M2 polarization

Siyu Fan
Cunliang Zhang
Runzhi Deng
ResearchOpen Access31 Aug 2024
Scientific Reports

Volume: 14, P: 1-11
Leukocyte immunoglobulin-like receptor B1 (LILRB1) protects human multiple myeloma cells from ferroptosis by maintaining cholesterol homeostasis

Patients with multiple myeloma need new therapeutic targets. The authors identify the transmembrane receptor LILRB1 as a potential target as it protects myeloma cells from ferroptosis by facilitating cholesterol uptake and maintaining cholesterol homeostasis and squalene levels.

Miao Xian
Qiang Wang
Qing Yi
ResearchOpen Access09 Jul 2024
Nature Communications

Volume: 15, P: 1-18
Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase

Dysfunction of enteropeptidase (EP) can result in pancreatitis, a life-threatening disease. Yang et al. report a series of EP structures representing the EP catalytic cycle and propose a mechanistic model of enzyme function.

Xiaoli Yang
Zhanyu Ding
Haojie Huang
ResearchOpen Access14 Nov 2022
Nature Communications

Volume: 13, P: 1-9
Sustained supershear rupture during the 2025 Mandalay, Myanmar earthquake

The Mw 7.7 2025 Mandalay earthquake displayed initial bilateral sub-shear rupture which then transitioned into sustained super-shear in the southward propagation direction, according to a combination of geodetic, finite fault inversion, back-projection and dynamic rupture analyses

Yanchuan Li
Xinjian Shan
Haicheng Xiong
ResearchOpen Access02 Dec 2025
Communications Earth & Environment

Volume: 6, P: 1-9
Boosting a practical Li-CO₂ battery through dimerization reaction based on solid redox mediator

Li–CO₂ batteries following Li₂CO₃-product route suffers from low output voltage and severe parasitic reactions. Here, the authors introduce a copper-based solid redox mediator in Li–CO₂ batteries with an efficient Li₂C₂O₄ product route to circumvent the shuttle effect and sluggish kinetics caused by soluble mediators.

Wei Li
Menghang Zhang
Haoshen Zhou
ResearchOpen Access27 Jan 2024
Nature Communications

Volume: 15, P: 1-11
Crop rotation and native microbiome inoculation restore soil capacity to suppress a root disease

Crop rotation helps preventing pathogen infestations compared to monocultures, which may be partly due to root-associated microbes. Here, the authors show that rhizosphere microbiomes in monocultures are less able to suppress fungal pathogens compared to crop rotations, and that inoculating certain microbes can mitigate it.

Yanyan Zhou
Zhen Yang
Xiaogang Li
ResearchOpen Access08 Dec 2023
Nature Communications

Volume: 14, P: 1-14
Ultraviolet Laser-induced ignition of RDX single crystal

Zhonghua Yan
Chuanchao Zhang
Xiaotao Zu
ResearchOpen Access05 Feb 2016
Scientific Reports

Volume: 6, P: 1-6
Immature characteristics of the East Anatolian Fault Zone from SAR, GNSS and strong motion data of the 2023 Türkiye–Syria earthquake doublet

Jiao Liu
Chuanchao Huang
Tuncay Taymaz
ResearchOpen Access09 May 2024
Scientific Reports

Volume: 14, P: 1-12
Exosomes derived from M2 macrophage promote HUVECs proliferation, migration and tube formation in vitro

Yiwen Xue
Jingru Chen
Jing Hao
ResearchOpen Access22 May 2025
Scientific Reports

Volume: 15, P: 1-11
Spatially informed graph transformers for spatially resolved transcriptomics

Spatially informed Graph Transformer integrates gene expression and spatial context to accurately denoise data and identify fine-grained tissue domains.

Xinyu Bao
Xiaosheng Bai
Chuanchao Zhang
ResearchOpen Access06 Apr 2025
Communications Biology

Volume: 8, P: 1-11
TMCO1 is essential for ovarian follicle development by regulating ER Ca²⁺ store of granulosa cells

Zhongshuai Sun
Hui Zhang
Tie-Shan Tang
ResearchOpen Access21 Feb 2018
Cell Death & Differentiation

Volume: 25, P: 1686-1701
Anti-oncogene PTPN13 inactivation by hepatitis B virus X protein counteracts IGF2BP1 to promote hepatocellular carcinoma progression

Yongcong Yan
Pinbo Huang
Zhiyu Xiao
ResearchOpen Access13 Oct 2020
Oncogene

Volume: 40, P: 28-45

Search

Adoptively transferred tumor-specific IL-9-producing cytotoxic CD8⁺ T cells activate host CD4⁺ T cells to control tumors with antigen loss

Realizing four-electron conversion chemistry for all-solid-state Li||I₂ batteries at room temperature

Metformin enhances osteogenic differentiation of BMSC by modulating macrophage M2 polarization

Leukocyte immunoglobulin-like receptor B1 (LILRB1) protects human multiple myeloma cells from ferroptosis by maintaining cholesterol homeostasis

Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase

Sustained supershear rupture during the 2025 Mandalay, Myanmar earthquake

Boosting a practical Li-CO₂ battery through dimerization reaction based on solid redox mediator

Crop rotation and native microbiome inoculation restore soil capacity to suppress a root disease

Ultraviolet Laser-induced ignition of RDX single crystal

Immature characteristics of the East Anatolian Fault Zone from SAR, GNSS and strong motion data of the 2023 Türkiye–Syria earthquake doublet

Exosomes derived from M2 macrophage promote HUVECs proliferation, migration and tube formation in vitro

Spatially informed graph transformers for spatially resolved transcriptomics

TMCO1 is essential for ovarian follicle development by regulating ER Ca²⁺ store of granulosa cells

Anti-oncogene PTPN13 inactivation by hepatitis B virus X protein counteracts IGF2BP1 to promote hepatocellular carcinoma progression

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