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Nature Communications (3)
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Showing 1–4 of 4 results

Advanced filters: Author: Chulei Cao Clear advanced filters

Crystal structures and snapshots along Tpt1-catalyzed phosphate transfer from nucleic acid to NAD⁺

Tpt1 family proteins are highly conserved and play essential roles in nucleic acid phosphate transfer in an NAD + -dependent manner. Here, the authors present several crystal structures of TkoTpt1 and reaffirm the two-step catalytic mechanism of the Tpt1-catalyzed reactions.

Chulei Cao
Jie Yang
Jianhua Gan
ResearchOpen Access04 Dec 2025
Nature Communications

Volume: 16, P: 1-14
Structures of African swine fever virus topoisomerase complex and their implications

African swine fever virus Topoisomerase II (AsfvTopII) is essential for the replication of the virus. Here, the authors present several crystal structures and provide mechanistic insights into substrate binding and cleavage by the AsfvTopII protein.

Jie Yang
Zhiwei Shao
Jianhua Gan
ResearchOpen Access01 Aug 2024
Nature Communications

Volume: 15, P: 1-10
Crystal structures and insights into precursor tRNA 5’-end processing by prokaryotic minimal protein-only RNase P

HARP are member of protein-only RNase P, which catalyzes pre-tRNA 5’-end processing and maturation. Here, the authors present crystal structure and provide mechanistic insights into pre-tRNA binding and cleavage by HARP proteins.

Yangyang Li
Shichen Su
Jianhua Gan
ResearchOpen Access28 Apr 2022
Nature Communications

Volume: 13, P: 1-13
Structural and functional insights into the helicase protein E5 of Mpox virus

Weizhen Zhang
Yusong Liu
Jianhua Gan
ResearchOpen Access25 Jun 2024
Cell Discovery

Volume: 10, P: 1-17