Previous studies have implicated interleukin-24 (IL-24) in neutrophilic asthma. Here the authors show the function of IL-24 release from eosinophils in eosinophilic asthma in mouse models of asthma and that IL-24 promotes eosinophil recruitment to the lungs and is involved in disruption of epithelial barrier integrity.
- Yi-Rou Wu
- Chung-Hsi Hsing
- Yu-Hsiang Hsu