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Showing 1–11 of 11 results
Advanced filters: Author: Claudia Kathe Clear advanced filters

  • The authors summarize changes in circuits after spinal cord injury and current strategies to target these circuits in order to improve recovery, but also advocate for new concepts of reorganizing circuits informed by multi-omic single-cell atlases.

    • Mark A. Anderson
    • Jordan W. Squair
    • Grégoire Courtine
    Reviews
    Nature Neuroscience
    Volume: 25, P: 1584-1596

  • The neuronal architecture that develops after spinal cord injury and causes autonomic dysreflexia is uncovered.

    • Jan Elaine Soriano
    • Remi Hudelle
    • Gregoire Courtine
    ResearchOpen Access
    Nature
    Volume: 646, P: 1167-1177

  • Transcriptomic analysis following epidural electrical stimulation of the lumbar spinal cord during neurorehabilitation in mice identifies a population of neurons that orchestrates the restoration of walking following paralysis.

    • Claudia Kathe
    • Michael A. Skinnider
    • Grégoire Courtine
    ResearchOpen Access
    Nature
    Volume: 611, P: 540-547

  • Whole-brain anatomical and activity surveys identify the lateral hypothalamus as a key driver of recovery from spinal cord injury, leading to a deep brain stimulation therapy that augments the recovery of walking in humans.

    • Newton Cho
    • Jordan W. Squair
    • Grégoire Courtine
    Research
    Nature Medicine
    Volume: 30, P: 3676-3686

  • The Tabulae Paralytica, a compilation of four molecular atlases of spinal cord injury, provides a window into the pathobiology of spinal cord injury, establishing a framework for integrating multimodal, genome-scale measurements in four dimensions to study biology and medicine.

    • Michael A. Skinnider
    • Matthieu Gautier
    • Grégoire Courtine
    Research
    Nature
    Volume: 631, P: 150-163

  • Differential expression analysis of single-cell transcriptomics allows scientists to dissect cell-type-specific responses to biological perturbations. Here, the authors show that many commonly used methods are biased and can produce false discoveries.

    • Jordan W. Squair
    • Matthieu Gautier
    • Grégoire Courtine
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-15

  • The cell types affected by biological perturbations in complex tissues are uncovered by single-cell analysis.

    • Michael A. Skinnider
    • Jordan W. Squair
    • Grégoire Courtine
    Research
    Nature Biotechnology
    Volume: 39, P: 30-34