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Showing 1–5 of 5 results
Advanced filters: Author: Coen van Solingen Clear advanced filters

  • In this Review, Moore and co-workers provide an overview of the mechanisms and functions of microRNAs and long non-coding RNAs in vascular biology and the regulation of lipid metabolism, as well as the effects of non-coding RNAs on atherosclerotic plaque formation and progression.

    • Tamer Sallam
    • Coen van Solingen
    • Kathryn J. Moore
    Reviews
    Nature Reviews Cardiology
    P: 1-22

  • Maintenance of cholesterol homeostasis is essential to human health. Here, the authors identify and characterize a primate-specific long noncoding RNA, called CHROME, that controls cholesterol homeostasis through fine-tuning of miRNAs and whose levels are elevated in human atherosclerosis.

    • Elizabeth J. Hennessy
    • Coen van Solingen
    • Kathryn J. Moore
    Research
    Nature Metabolism
    Volume: 1, P: 98-110

  • By reprogramming innate immune cells to an immunosuppressive phenotype, myocardial infarction accelerates breast cancer progression in mice, and the clinical relevance of these findings was demonstrated in individuals with early-stage breast cancer who experienced cardiovascular events after cancer diagnosis.

    • Graeme J. Koelwyn
    • Alexandra A. C. Newman
    • Kathryn J. Moore
    Research
    Nature Medicine
    Volume: 26, P: 1452-1458