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Showing 1–11 of 11 results
Advanced filters: Author: Connie B. Roth Clear advanced filters

  • The risk of developing active tuberculosis (TB) in individuals with latent TB infection is highly variable within and among different risk groups. A personalized risk predictor was developed to better target preventative treatment to individuals at greatest risk, supporting evidence-based clinical decision-making for latent TB.

    • Rishi K. Gupta
    • Claire J. Calderwood
    • Ibrahim Abubakar
    Research
    Nature Medicine
    Volume: 26, P: 1941-1949

  • Jayavelu, Samaha et al., apply machine learning models on hospital admission data, including antibody titers and viral load, to identify patients at high risk for Long COVID. Low antibody levels, high viral loads, chronic diseases, and female sex are key predictors, supporting early, targeted interventions.

    • Naresh Doni Jayavelu
    • Hady Samaha
    • Matthew C. Altman
    ResearchOpen Access
    Communications Medicine
    Volume: 6, P: 1-10

  • Solid organ transplant recipients are at increased risk of infectious disease and have unique molecular pathophysiology. Here the authors use host-microbe profiling to assess SARS-CoV-2 infection and immunity in solid organ transplant recipients, showing enhanced viral abundance, impaired clearance, and increased expression of innate immunity genes.

    • Harry Pickering
    • Joanna Schaenman
    • Charles R. Langelier
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16

  • The role of IgG glycosylation in the immune response has been studied, but less is known about IgM glycosylation. Here the authors characterize glycosylation of SARS-CoV-2 spike specific IgM and show that it correlates with COVID-19 severity and affects complement deposition.

    • Benjamin S. Haslund-Gourley
    • Kyra Woloszczuk
    • Mary Ann Comunale
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-19

  • Post-acute sequelae of SARS-CoV-2 (PASC) is still not well understood. Here the authors provide patient reported outcomes from 590 hospitalized COVID-19 patients and show association of PASC with higher respiratory SARS-CoV-2 load and circulating antibody titers, and in some an elevation in circulating fibroblast growth factor 21.

    • Al Ozonoff
    • Naresh Doni Jayavelu
    • Nadine Rouphael
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-17

  • Physical vapour deposition of small-molecule glass formers onto soft substrates enhances the local dynamics at the top free surface, leading to the formation of denser glasses and providing access to states deeper in the potential energy landscape.

    • Connie B. Roth
    News & Views
    Nature Materials
    Volume: 23, P: 587-588

  • In this article, the authors review the current understanding of the molecular mechanisms underlying cell type identity and discuss how new phenotypic features of cell types evolve. They explain how evolutionary lineage differs from developmental lineage and highlight how an evolutionary view of cell type identity can facilitate research in comparative cell biology.

    • Detlev Arendt
    • Jacob M. Musser
    • Günter P. Wagner
    Reviews
    Nature Reviews Genetics
    Volume: 17, P: 744-757