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Showing 1–2 of 2 results
Advanced filters: Author: Connor Criswell Clear advanced filters

  • The combination of computational design, laboratory-based screening and biophysical validation enables the de novo generation of variable heavy-chain antibody fragments and antibodies that precisely target chosen disease-related molecules.

    • Nathaniel R. Bennett
    • Joseph L. Watson
    • David Baker
    ResearchOpen Access
    Nature
    Volume: 649, P: 183-193

  • Regulation of gene expression is a facet of human brain specialization. Here, the authors show that human-like expression of the CLOCK gene in the mouse neocortex enhances cognitive flexibility and neural connectivity, suggesting an evolutionary gain of function that may have contributed to human cognitive specialization.

    • Yuxiang Liu
    • Miles R. Fontenot
    • Genevieve Konopka
    Research
    Nature Neuroscience
    Volume: 28, P: 1716-1728