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Precise and scalable self-organization in mammalian pseudo-embryos

Examining artificial embryos (gastruloids), Merle et al. uncover precise gene organization and proportional growth, providing insights into fundamental principles of developmental processes in mammalian systems.

Mélody Merle
Leah Friedman
Thomas Gregor
Research15 Mar 2024
Nature Structural & Molecular Biology

Volume: 31, P: 896-902
Highly efficient radiosensitization of human glioblastoma and lung cancer cells by a G-quadruplex DNA binding compound

Patrick Merle
Marine Gueugneau
Andreï Tchirkov
ResearchOpen Access06 Nov 2015
Scientific Reports

Volume: 5, P: 1-11
Depletion of slow-cycling PDGFRα⁺ADAM12⁺ mesenchymal cells promotes antitumor immunity by restricting macrophage efferocytosis

Peduto and colleagues report a role for ADAM12⁺ mesenchymal stromal cells at the tumor margins and their interaction with immune cells to promote a permissive ‘protumor’ environment.

Selene E. Di Carlo
Jerome Raffenne
Lucie Peduto
ResearchOpen Access05 Oct 2023
Nature Immunology

Volume: 24, P: 1867-1878
Mycobacterium tuberculosis precursor rRNA as a measure of treatment-shortening activity of drugs and regimens

It is unclear why different antibiotics vary in their ability to shorten treatment of tuberculosis. Here, the authors show that a measure based on ribosomal RNA synthesis in Mycobacterium tuberculosis correlates with treatment shortening in culture, in mice and in human studies.

Nicholas D. Walter
Sarah E. M. Born
Martin I. Voskuil
ResearchOpen Access18 May 2021
Nature Communications

Volume: 12, P: 1-11
Classification of GBA1 variants and their impact on Parkinson’s disease: an in silico score analysis

Aymeric Lanore
Christelle Tesson
Eva Camgrand
ResearchOpen Access02 Aug 2025
npj Parkinson's Disease

Volume: 11, P: 1-14
Author Correction: Classification of GBA1 variants and their impact on Parkinson’s disease: an in silico score analysis

Aymeric Lanore
Christelle Tesson
Eva Camgrand
Amendments and CorrectionsOpen Access21 Nov 2025
npj Parkinson's Disease

Volume: 11, P: 1

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Precise and scalable self-organization in mammalian pseudo-embryos

Highly efficient radiosensitization of human glioblastoma and lung cancer cells by a G-quadruplex DNA binding compound

Depletion of slow-cycling PDGFRα⁺ADAM12⁺ mesenchymal cells promotes antitumor immunity by restricting macrophage efferocytosis

Mycobacterium tuberculosis precursor rRNA as a measure of treatment-shortening activity of drugs and regimens

Classification of GBA1 variants and their impact on Parkinson’s disease: an in silico score analysis

Author Correction: Classification of GBA1 variants and their impact on Parkinson’s disease: an in silico score analysis

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Precise and scalable self-organization in mammalian pseudo-embryos

Highly efficient radiosensitization of human glioblastoma and lung cancer cells by a G-quadruplex DNA binding compound

Depletion of slow-cycling PDGFRα+ADAM12+ mesenchymal cells promotes antitumor immunity by restricting macrophage efferocytosis

Mycobacterium tuberculosis precursor rRNA as a measure of treatment-shortening activity of drugs and regimens

Classification of GBA1 variants and their impact on Parkinson’s disease: an in silico score analysis

Author Correction: Classification of GBA1 variants and their impact on Parkinson’s disease: an in silico score analysis

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Depletion of slow-cycling PDGFRα⁺ADAM12⁺ mesenchymal cells promotes antitumor immunity by restricting macrophage efferocytosis