Bai et al. present a novel mRNA rabies vaccine, RABV-G-LT, which combines glycoprotein and T-cell immunogens to enhance protection against rabies. This dual-immunogen approach elicits robust neutralizing antibodies and T-cell responses in mice and non-human primates, providing a promising strategy for more effective and cost-efficient rabies prevention.
- Shimeng Bai
- Xinghao Pan
- Jianqing Xu
