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Showing 1–50 of 357 results

Advanced filters: Author: D. Raynaud Clear advanced filters

Author Correction: Raynaud phenomenon and digital ulcers in systemic sclerosis

Michael Hughes
Yannick Allanore
Marco Matucci-Cerinic
Amendments and Corrections09 Mar 2021
Nature Reviews Rheumatology

Volume: 17, P: 246
Raynaud phenomenon and digital ulcers in systemic sclerosis

Raynaud phenomenon and digital ulcers are some of the most common and difficult to treat manifestations of systemic sclerosis. In this Review, the authors outline how to assess and treat these conditions, and also discuss unmet clinical needs.

Michael Hughes
Yannick Allanore
Marco Matucci-Cerinic
Reviews25 Feb 2020
Nature Reviews Rheumatology

Volume: 16, P: 208-221
Disproportionality analysis of Raynaud’s phenomenon associated with calcitonin gene-related peptide inhibitors using the Food and Drug Administration adverse event reporting system

Nai Lee
Ji Hoon Ok
Yun Kim
ResearchOpen Access15 Feb 2025
Scientific Reports

Volume: 15, P: 1-13
A vascular mechanistic approach to understanding Raynaud phenomenon

This article places Raynaud phenomenon in the context of a mechanistic understanding of cutaneous vasoconstrictive and thermoregulatory processes, describing how these processes might regulate the pathogenesis of Raynaud phenomenon and ultimately inform new approaches to its treatment.

Nicholas A. Flavahan
Reviews23 Dec 2014
Nature Reviews Rheumatology

Volume: 11, P: 146-158
Glutathione S-transferase M1 and GST T1 genetic polymorphisms and Raynaud’s phenomenon in French vinyl chloride monomer-exposed workers

Luc Fontana
Marie-Jeanne Marion
Pierre Catilina
Research01 Oct 2006
Journal of Human Genetics

Volume: 51, P: 879-886
Extending the Vostok ice-core record of palaeoclimate to the penultimate glacial period

J. Jouzel
N. I. Barkov
P. Yiou
Research29 Jul 1993
Nature

Volume: 364, P: 407-412
Optimized treatment algorithms for digital vasculopathy in SSc

Early identification of secondary Raynaud phenomenon is essential to treat the underlying disease—most frequently systemic sclerosis (SSc). Integrated therapeutic approaches and monitoring systems that offer improved modalities of care feature in the new best practice recommendations for the treatment of digital vasculopathy in SSc.

Maurizio Cutolo
Alberto Sulli
News & Views11 Aug 2015
Nature Reviews Rheumatology

Volume: 11, P: 569-571
Corticosteroid-binding globulin and corticosterone interaction with progesterone receptors

J. P. RAYNAUD
M. MOGUILEWSKY
Research14 May 1981
Nature

Volume: 291, P: 171-172
Powerful New Inhibitor of Murine Leukaemia and Sarcoma Viruses

J. C. CHERMANN
M. RAYNAUD
G. MATHÉ
Research11 Jul 1970
Nature

Volume: 227, P: 173-174
Corticosteroid-binding globulin and corticosterone interaction with progesterone receptors (reply)

B. D. GREENSTEIN
H. AL-KHOURI
Research14 May 1981
Nature

Volume: 291, P: 172
The role of deep roots in the hydrological and carbon cycles of Amazonian forests and pastures

Daniel C. Nepstad
Claudio R. de Carvalho
Simone Vieira
Research15 Dec 1994
Nature

Volume: 372, P: 666-669
Synchronous changes in atmospheric CH4 and Greenland climate between 40 and 8 kyr BP

J. Chappellaz
T. Bluniert
B. Stauffert
Research02 Dec 1993
Nature

Volume: 366, P: 443-445
A 150,000-year climatic record from Antarctic ice

C. Lorius
J. Jouzel
V. M. Kotlyakov
Research01 Aug 1985
Nature

Volume: 316, P: 591-596
Vostok ice core provides 160,000-year record of atmospheric CO₂

J. M. Barnola
D. Raynaud
C. Lorius
Research01 Oct 1987
Nature

Volume: 329, P: 408-414
Marine barite as a monitor of seawater strontium isotope composition

A. Paytan
M. Kastner
T. Herbert
Research02 Dec 1993
Nature

Volume: 366, P: 445-449
Climatic and CH₄ cycle implications of glacial–interglacial CH₄ change in the Vostok ice core

D. Raynaud
J. Chappellaz
C. Lorius
Research16 Jun 1988
Nature

Volume: 333, P: 655-657
Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5

Kirk L. Clark
Elaine D Halay
Stephen K Burley
Research29 Jul 1993
Nature

Volume: 364, P: 412-420
Total gas content and surface elevation of polar ice sheets

D. Raynaud
B. Lebel
Research27 Sept 1979
Nature

Volume: 281, P: 289-291
Vostok ice core: a continuous isotope temperature record over the last climatic cycle (160,000 years)

J. Jouzel
C. Lorius
V. M. Petrov
Research01 Oct 1987
Nature

Volume: 329, P: 403-408
Palaeoclimatological and chronological implications of the Vostok core dust record

J. R. Petit
L. Mourner
C. Lorius
Research04 Jan 1990
Nature

Volume: 343, P: 56-58
Isotopic composition of atmospheric CO₂ inferred from carbon in C4 plant cellulose

Bruno D. Marino
Michael B. McElroy
Research10 Jan 1991
Nature

Volume: 349, P: 127-131
An update on autoantibodies in the idiopathic inflammatory myopathies

This Review provides an update on autoantibodies associated with idiopathic inflammatory myopathies in both adults and children. The authors also discuss methods of autoantibody detection and the advantages and limitations of each technique.

Nur Azizah Allameen
Ana Isabel Ramos-Lisbona
David A. Isenberg
Reviews28 Nov 2024
Nature Reviews Rheumatology

Volume: 21, P: 46-62
Targeted therapy for systemic sclerosis: how close are we?

Systemic sclerosis is complex disease for which effective therapies remain elusive. In this Review article, Ramos-Casals and colleagues highlight therapeutic approaches to the treatment of systemic sclerosis, and suggest that the future of systemic sclerosis therapy might be as multifaceted as the disease itself.

Manuel Ramos-Casals
Vicent Fonollosa-Pla
Antoni Sisó-Almirall
Reviews13 Apr 2010
Nature Reviews Rheumatology

Volume: 6, P: 269-278
Atmospheric gas concentrations over the past century measured in air from firn at the South Pole

M. Battle
M. Bender
A. D. Clarket
Research19 Sept 1996
Nature

Volume: 383, P: 231-235
An Antarctic ice core reveals atmospheric CO₂ variations over the past few centuries

D. Raynaud
J. M. Barnola
Research23 May 1985
Nature

Volume: 315, P: 309-311
Ice-core record of atmospheric methane over the past 160,000 years

J. Chappellaz
J. M. Barnola
C. Lorius
Research10 May 1990
Nature

Volume: 345, P: 127-131
Long-term sequelae of treatment for testicular germ cell tumours

D Bissett
L Kunkeler
SB Kaye
Research01 Oct 1990
British Journal of Cancer

Volume: 62, P: 655-659
The ice-core record: climate sensitivity and future greenhouse warming

C. Lorius
J. Jouzel
H. Le Treut
Reviews13 Sept 1990
Nature

Volume: 347, P: 139-145
Selenoprotein deficiency disorder predisposes to aortic aneurysm formation

Aortic aneurysms have a heritable basis. Here, the authors report that a selenoprotein deficiency disorder due to mutations in SECISBP2, causes oxidative stress-mediated aortic cell death, predisposing to thoracic aortic aneurysm formation.

Erik Schoenmakers
Federica Marelli
Krishna Chatterjee
ResearchOpen Access02 Dec 2023
Nature Communications

Volume: 14, P: 1-14
Sildenafil: from angina to erectile dysfunction to pulmonary hypertension and beyond

Phosphodiesterase 5 inhibitors augment endogenous nitric oxide signalling, thereby restoring vascular reactivity to diseased blood vessels. Ghofrani and colleagues review the evolution of the PDE5 inhibitor sildenafil from a potential anti-angina drug, to an on-demand oral treatment for erectile dysfunction, and its recent re-positioning as a pulmonary hypertension therapeutic.

Hossein A. Ghofrani
Ian H. Osterloh
Friedrich Grimminger
Reviews01 Aug 2006
Nature Reviews Drug Discovery

Volume: 5, P: 689-702
Comparison of CO₂ measurements by two laboratories on air from bubbles in polar ice

J. M. Barnola
D. Raynaud
H. Oeschger
Research02 Jun 1983
Nature

Volume: 303, P: 410-413
Elucidating molecularly stratified single agent, and combination, therapeutic strategies targeting MCL1 for lethal prostate cancer

Despite improving therapeutic options, the prognosis for patients with metastatic castration-resistance prostate cancer (mCRPC) remains poor. Here, the authors identify MCL1 copy number alterations as a prognostic and predictive biomarker, demonstrating its therapeutic potential as a drug target, either alone or in combination, in patients with mCRPC.

Juan M. Jiménez-Vacas
Daniel Westaby
Adam Sharp
ResearchOpen Access08 Oct 2025
Nature Communications

Volume: 16, P: 1-22
Fibroblast A20 governs fibrosis susceptibility and its repression by DREAM promotes fibrosis in multiple organs

A20 gene variants are linked with systemic sclerosis (SS), but the mechanisms are unclear. Here, the authors show that A20 expression is reduced in SS skin and lungs, that its ablation in mice induces SS, and that show that fibrosis can be ameliorated by induction of A20.

Wenxia Wang
Swarna Bale
John Varga
ResearchOpen Access26 Oct 2022
Nature Communications

Volume: 13, P: 1-16
Vascular aging in long-term survivors of testicular cancer more than 20 years after treatment with cisplatin-based chemotherapy

Johannes Stelwagen
Sjoukje Lubberts
Jourik A. Gietema
ResearchOpen Access14 Sept 2020
British Journal of Cancer

Volume: 123, P: 1599-1607
NMR based clinical metabolomics revealed altered lipid and sugar metabolism in systemic sclerosis with implications for diagnosis and therapeutic strategies

Gurvinder Singh
Sakir Ahmed
Dinesh Kumar
ResearchOpen Access21 Aug 2025
Scientific Reports

Volume: 15, P: 1-13
Shelf sea fronts' adjustments revealed by satellite IR imagery

J. H. Simpson
D. Bowers
Research23 Aug 1979
Nature

Volume: 280, P: 648-651
Cytogenetic abnormalities associated with the t(12;21): a collaborative study of 169 children with t(12;21)-positive acute lymphoblastic leukemia

SD Raynaud
N Dastugue
SC Raimondi
Research09 Sept 1999
Leukemia

Volume: 13, P: 1325-1330
An oxygen-isotope climatic record from the Devon Island ice cap, arctic Canada

W. S. B. Paterson
R. M. Koerner
H. Oeschger
Research07 Apr 1977
Nature

Volume: 266, P: 508-511
Climate forcing implications from Vostok ice-core sulphate data

M. R. Legrand
R. J. Delmas
R. J. Charlson
Research01 Aug 1988
Nature

Volume: 334, P: 418-420
Cortisol Binding to Proteins in Plasma in the Human Neonate and Infant

A J Hadjian
M Chedin
E M Chambaz
Research01 Jan 1975
Pediatric Research

Volume: 9, P: 40-45
Action of formamidine pesticides on octopamine receptors

Peter D. Evans
Julian D. Gee
Research04 Sept 1980
Nature

Volume: 287, P: 60-62
Role of corticosteroid-binding globulin in interaction of corticosterone with uterine and brain progesterone receptors

H. Al-Khouri
B. D. Greenstein
Research04 Sept 1980
Nature

Volume: 287, P: 58-60
Thyroid growth-blocking antibodies in primary myxoedema

H. A. Drexhage
G. F. Bottazzo
D. Doniach
Research12 Feb 1981
Nature

Volume: 289, P: 594-596
An automated histological classification system for precision diagnostics of kidney allografts

A decision-support system that automates the Banff classification system for diagnosis of kidney allograft rejection leads to reclassification and correction of pathologists’ diagnoses and improves risk stratification of allograft outcomes.

Daniel Yoo
Valentin Goutaudier
Alexandre Loupy
Research04 May 2023
Nature Medicine

Volume: 29, P: 1211-1220
D25V apolipoprotein C-III variant causes dominant hereditary systemic amyloidosis and confers cardiovascular protective lipoprotein profile

Decrease in Apolipoprotein C-III (ApoC-III) yields a cardioprotective lipoprotein profile. Here, Valleix et al.reveal a novel ApoC-III variant conferring low plasma ApoC-III concentration and cardioprotection despite renal insufficiency, and, unexpectedly, causing dominant hereditary systemic amyloidosis due to its fibrillogenic nature.

Sophie Valleix
Guglielmo Verona
Vittorio Bellotti
ResearchOpen Access21 Jan 2016
Nature Communications

Volume: 7, P: 1-14
Measurements of methanesulphonic acid in Antarctic ice

C. Saigne
M. Legrand
Research19 Nov 1987
Nature

Volume: 330, P: 240-242
A computational framework for defining and validating reproducible phenotyping algorithms of 313 diseases in the UK Biobank

Ana Torralbo
Jonathan M. Davitte
Spiros Denaxas
ResearchOpen Access09 Jul 2025
Scientific Reports

Volume: 15, P: 1-17
TRPA1 is essential for the vascular response to environmental cold exposure

Blood flow in the skin of mammals changes in response to cold, but the mechanisms driving this response are unclear. Aubdool et al. show that the non-selective cation channel, TRPA1, is a vascular cold sensor and required for the vascular protective response to local cold exposure.

Aisah A. Aubdool
Rabea Graepel
Susan D. Brain
ResearchOpen Access11 Dec 2014
Nature Communications

Volume: 5, P: 1-13
Unchanged Rate of Brain Serotonin Synthesis during Chronic Morphine Treatment and Failure of Parachlorophenylalanine to attenuate Withdrawal Syndrome in Mice

IAN MARSHALL
D. G. GRAHAME-SMITH
Research19 Dec 1970
Nature

Volume: 228, P: 1206-1208
Four climate cycles in Vostok ice core

J. R. Petit
I. Basile
V. Kotlyakov
Research22 May 1997
Nature

Volume: 387, P: 359-360

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