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Showing 1–2 of 2 results
Advanced filters: Author: Danguole Norkunaite Clear advanced filters

  • A single-cell sequencing study using more than 30,000 tumour genomes from human ovarian cancers shows that whole-genome doubling is an ongoing mutational process that drives tumour evolution and disrupts immunity.

    • Andrew McPherson
    • Ignacio Vázquez-García
    • Sohrab P. Shah
    ResearchOpen Access
    Nature
    Volume: 644, P: 1078-1087

  • Missegregated chromosomes that are sequestrated in micronuclei are subject to changes in histone modifications leading to abnormalities in chromatin accessibility that remain long after the chromosomes have been reincorporated into the primary nucleus.

    • Albert S. Agustinus
    • Duaa Al-Rawi
    • Samuel F. Bakhoum
    ResearchOpen Access
    Nature
    Volume: 619, P: 176-183