Nature Search

Treatment of multiple sclerosis with T–cell receptor peptides: Results of a double–blind pilot trial

Arthur A. Vandenbark
Yuan K. Chou
Dennis N. Bourdette
Research01 Oct 1996
Nature Medicine

Volume: 2, P: 1109-1115
Global, regional, and national burden of chronic respiratory diseases and impact of the COVID-19 pandemic, 1990–2023: a Global Burden of Disease study

Estimates from the Global Burden of Disease study reveal declines in chronic respiratory disease mortality between 1990 and 2023—especially during the COVID-19 pandemic—but the burdens on people affected remain substantial.

Jiyeon Oh
Soeun Kim
Dong Keon Yon
Research06 Jan 2026
Nature Medicine

Volume: 32, P: 197-223
Visualizing the formation of an RNA folding intermediate through a fast highly modular secondary structure switch

Short-lived RNA folding intermediates have important roles in the folding of RNA. Here, the authors combine ¹⁵N relaxation dispersion NMR with chemical probing to visualise one of these intermediates, and are able to show it is a secondary structural switch, that might help with folding.

Yi Xue
Brant Gracia
Hashim M. Al-Hashimi
ResearchOpen Access13 Jun 2016
Nature Communications

Volume: 7, P: 1-11
Reversal of Phencyclidine-Induced Hyperactivity by Glycine and the Glycine Uptake Inhibitor Glycyldodecylamide

Daniel C Javitt
Henry Sershen
Abel Lajtha
Research01 Sept 1997
Neuropsychopharmacology

Volume: 17, P: 202-204
Rapid and accurate determination of atomistic RNA dynamic ensemble models using NMR and structure prediction

Determining dynamic ensembles of biomolecules is still challenging. Here the authors present an approach for rapid RNA ensemble determination that combines RNA structure prediction tools and NMR residual dipolar coupling data and use it to determine atomistic ensemble models for a variety of RNAs.

Honglue Shi
Atul Rangadurai
Hashim M. Al-Hashimi
ResearchOpen Access02 Nov 2020
Nature Communications

Volume: 11, P: 1-14
Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike-induced syncytia

Lungs from patients who died from COVID-19 show atypical fused cells, the formation of which is mediated by the SARS-CoV-2 spike protein, and drugs that inhibit TMEM16F can prevent spike-induced syncytia formation.

Luca Braga
Hashim Ali
Mauro Giacca
Research07 Apr 2021
Nature

Volume: 594, P: 88-93
N1-Methylpseudouridine and pseudouridine modifications modulate mRNA decoding during translation

Chemical modification of mRNA nucleobases alters hydrogen bonding during translation. Here the authors show that the N1-methylpseudouridine (m1ψ), used in therapeutics, does not change translation rate but modestly modulates its fidelity in a codon-position and tRNA dependent manner.

Jeremy Monroe
Daniel E. Eyler
Kristin S. Koutmou
ResearchOpen Access16 Sept 2024
Nature Communications

Volume: 15, P: 1-11
RNA conformational propensities determine cellular activity

Systematic alteration of HIV-1 TAR RNA and quantitative determination of its propensity to bind to the Tat protein establish a key role role for a rare and short-lived RNA state in Tat-dependent transactivation in cells.

Megan L. Ken
Rohit Roy
Hashim M. Al-Hashimi
Research17 May 2023
Nature

Volume: 617, P: 835-841
Structure determination of high-energy states in a dynamic protein ensemble

Combining NMR spectroscopy-derived pseudocontact shifts (PCSs) with Carr–Purcell–Meiboom–Gill (CPMG) relaxation dispersion enables protein structure determination of lowly populated high-energy states that are essential for macromolecular function.

John B. Stiller
Renee Otten
Dorothee Kern
Research02 Mar 2022
Nature

Volume: 603, P: 528-535
A multinational cross-sectional study on the prevalence and predictors of long COVID across 33 countries

Mohamed Sayed Zaazouee
Eman Ayman Nada
Mohamed Onyango
ResearchOpen Access03 Aug 2025
Scientific Reports

Volume: 15, P: 1-13
Author Correction: Scalable and robust SARS-CoV-2 testing in an academic center

Jim Aitken
Karen Ambrose
Rachel Zillwood
Amendments and Corrections17 Jul 2020
Nature Biotechnology

Volume: 38, P: 1000
The roles of structural dynamics in the cellular functions of RNAs

The functions of many regulatory RNAs depend on how their 3D structure changes in response to cellular conditions. Recent studies have revealed that RNA exists as a dynamic ensemble of conformations, which form with different probabilities in different cellular conditions and thus modulate RNA function.

Laura R. Ganser
Megan L. Kelly
Hashim M. Al-Hashimi
Reviews10 Jun 2019
Nature Reviews Molecular Cell Biology

Volume: 20, P: 474-489
Covalently bonded three-dimensional carbon nanotube solids via boron induced nanojunctions

Daniel P. Hashim
Narayanan T. Narayanan
Pulickel M. Ajayan
ResearchOpen Access13 Apr 2012
Scientific Reports

Volume: 2, P: 1-8
Focal therapy compared to radical prostatectomy for non-metastatic prostate cancer: a propensity score-matched study

Taimur T. Shah
Deepika Reddy
Mathias Winkler
Research28 Jan 2021
Prostate Cancer and Prostatic Diseases

Volume: 24, P: 567-574
Modulation of Striatal Dopamine Release by Glycine Transport Inhibitors

Daniel C Javitt
Audrey Hashim
Henry Sershen
Research26 Jan 2005
Neuropsychopharmacology

Volume: 30, P: 649-656
A physical sciences network characterization of non-tumorigenic and metastatic cells

David B. Agus
Jenolyn F. Alexander
Pei-Hsun Wu
ResearchOpen Access26 Apr 2013
Scientific Reports

Volume: 3, P: 1-12
Neurofilament light interaction with GluN1 modulates neurotransmission and schizophrenia-associated behaviors

Aidong Yuan
Veeranna
Ralph A. Nixon
ResearchOpen Access24 Aug 2018
Translational Psychiatry

Volume: 8, P: 1-12
Sustained high blood pressure and 24-h ambulatory blood pressure monitoring in Tanzanian adolescents

Mussa K. Nsanya
Philip Ayieko
Robert N. Peck
ResearchOpen Access16 Apr 2021
Scientific Reports

Volume: 11, P: 1-9
Fibrous dolomite formation at a Miocene methane seep may reflect Neoproterozoic aragonite-dolomite sea conditions

Identification of fibrous dolomite in a Miocene methane seep limestone deposit in Italy, using synchrotron X-ray diffraction and optical observations, offers insights into the formation processes of older fibrous dolomite in the Neoproterozoic

Yang Lu
Carsten Paulmann
Jörn Peckmann
ResearchOpen Access02 Oct 2023
Communications Earth & Environment

Volume: 4, P: 1-8
Scalable and robust SARS-CoV-2 testing in an academic center

Jim Aitken
Karen Ambrose
Rachel Zillwood
Correspondence18 Jun 2020
Nature Biotechnology

Volume: 38, P: 927-931

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