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Showing 151–200 of 311 results

Advanced filters: Author: David A. McCormick Clear advanced filters

A region within the third extracellular loop of rat Aquaporin 6 precludes trafficking to plasma membrane in a heterologous cell line

D. C. Soler
T. Kowatz
A. Vahedi-Faridi
ResearchOpen Access01 Jul 2021
Scientific Reports

Volume: 11, P: 1-8
Toll-like receptor 2 ligands on the staphylococcal cell wall downregulate superantigen-induced T cell activation and prevent toxic shock syndrome

Staphylococcal superantigens are potent activators of T cells, causing toxic shock syndrome and death. But surprisingly few staphylococcal infections of humans are associated with TSS, even though the bacteria produce the superantigen toxins. Joaquin Madrenas and his colleagues report that other components of the bacteria can downregulate the superantigen-induced T cell activation, protecting the host from death by TSS.

Thu A Chau
Michelle L McCully
Joaquín Madrenas
Research24 May 2009
Nature Medicine

Volume: 15, P: 641-648
Increased concentrations of phosphatidate, diacylglycerol and ceramide in ras- and tyrosine kinase (fps)-transformed fibroblasts

Ashley Martin
Patricia A Duffy
David N Brindley
Research03 Apr 1997
Oncogene

Volume: 14, P: 1571-1580
Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell lines

Edwina C Lerner
Ting-Ting Zhang
Saïd M Sebti
Research11 Sept 1997
Oncogene

Volume: 15, P: 1283-1288
Multiple plasma membrane reporters discern LHFPL5 region that blocks trafficking to the plasma membrane

David C. Soler
Angela Ballesteros
Ruben Stepanyan
ResearchOpen Access13 Feb 2023
Scientific Reports

Volume: 13, P: 1-8
Disposable ultrasound-sensing chronic cranial window by soft nanoimprinting lithography

Chronic cranial windows (CCW) enable long-term imaging of brain activity, but usually they only provide passive optical access to the tissue. Here the authors develop an active CCW integrated with an ultrasound detector which enables long-term photoacoustic imaging of the cortical vasculature in live mice with higher image quality.

Hao Li
Biqin Dong
Cheng Sun
ResearchOpen Access19 Sept 2019
Nature Communications

Volume: 10, P: 1-9
Author Correction: Measurement of the generalized spin polarizabilities of the neutron in the low-Q² region

Vincent Sulkosky
Chao Peng
Lingyan Zhu
Amendments and Corrections03 Mar 2022
Nature Physics

Volume: 18, P: 473
New roles for G-protein (βγ-dimers in transmembrane signalling

David E. Clapham
Eva J. Neer
Reviews30 Sept 1993
Nature

Volume: 365, P: 403-406
Are thalamocortical rhythms the rosetta stone of a subset of neurological disorders?

David A. McCormick
News & Views01 Dec 1999
Nature Medicine

Volume: 5, P: 1349-1351
Brain calculus: neural integration and persistent activity

Tank and colleagues make in vivo intracellular recordings from neurons in a 'neural integrator' of the goldfish involved in maintaining eye position. In this circuit, 'working' memory may be the result of persistent changes in the state of the local network.

David A. McCormick
News & Views01 Feb 2001
Nature Neuroscience

Volume: 4, P: 113-114
Sequential triage of transmembrane segments by Sec61α during biogenesis of a native multispanning membrane protein

Heather Sadlish
David Pitonzo
William R Skach
Research25 Sept 2005
Nature Structural & Molecular Biology

Volume: 12, P: 870-878
Arrays of individually controlled ions suitable for two-dimensional quantum simulations

Analogue quantum simulators could provide insights into complex dynamics, but realizing them in a scalable way remains a technological challenge. Here, the authors demonstrate how two-dimensional arrays of three ions trapped in individually controlled wells could form a scalable platform for quantum simulation.

Manuel Mielenz
Henning Kalis
Tobias Schaetz
ResearchOpen Access13 Jun 2016
Nature Communications

Volume: 7, P: 1-9
An electric-eel-inspired soft power source from stacked hydrogels

Miniature hydrogel compartments in scalable stacked and folded geometries were used to prepare a contact-activated artificial electric organ.

Thomas B. H. Schroeder
Anirvan Guha
Michael Mayer
Research14 Dec 2017
Nature

Volume: 552, P: 214-218
Cyclin-dependent kinase inhibitor indirubin-3′-oxime selectively inhibits human papillomavirus type 16 E7-induced numerical centrosome anomalies

Stefan Duensing
Anette Duensing
Karl Münger
Research20 Sept 2004
Oncogene

Volume: 23, P: 8206-8215
A case of ectopic dysplastic kidney and ectopic ureter diagnosed by MRI

This Case Study describes a 14-year-old girl with continuous urinary incontinence after resection of a vaginal septum associated with uterus didelphys. The authors discuss the diagnostic procedures undertaken, and show that MRI was effective, both preoperatively and intraoperatively, in detecting an ectopic ureter and ectopic dysplastic kidney.

David T Duong
Linda MD Shortliffe
Reviews07 Oct 2008
Nature Clinical Practice Urology

Volume: 5, P: 632-636
KRAS insertion mutations are oncogenic and exhibit distinct functional properties

Amino acid substitutions in K-Ras that constitutively activate the protein are common in cancer. Here, the authors describe mutations in the K-RasSwitch 2 domain and show that the mutant proteins accumulate in the active conformation, exhibit defective binding to PI3 kinase, and are hypersensitive to MEK inhibitors.

Yasmine White
Aditi Bagchi
Ari J. Firestone
ResearchOpen Access08 Feb 2016
Nature Communications

Volume: 7, P: 1-8
Assessment of brain penetration and tumor accumulation of niraparib and olaparib: insights from multimodal imaging in preclinical models

M. Reid Groseclose
Jeremy A. Barry
Hasan Alsaid
ResearchOpen Access29 Sept 2025
Scientific Reports

Volume: 15, P: 1-13
Chiral transcription in self-assembled tetrahedral Eu₄L₆ chiral cages displaying sizable circularly polarized luminescence

Controlling the chirality of self-assembled polyhedra is a synthetic challenge. Here, the authors stereoselectively form emissive lanthanide tetrahedral cages from a series of chiral ligands, and use their circularly polarized luminescence to explore the effect of ligand point chirality on supramolecular architecture.

Chi-Tung Yeung
King-Him Yim
Ga-Lai Law
ResearchOpen Access24 Oct 2017
Nature Communications

Volume: 8, P: 1-10
The dynamic, combinatorial cis-regulatory lexicon of epidermal differentiation

A deep-learning framework interprets multiomic data across epidermal differentiation, identifying cooperative DNA sequence rules that regulate gene modules. Massively parallel reporter assay analysis validates temporal dynamics and cis-regulatory logic.

Daniel S. Kim
Viviana I. Risca
Paul A. Khavari
Research14 Oct 2021
Nature Genetics

Volume: 53, P: 1564-1576
Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia

Analysis of bronchoalveolar lavage fluid samples from patients with SARS-CoV-2-induced respiratory failure suggests that SARS-CoV-2 infects alveolar macrophages to cause release of T cell chemoattractants, thereby inducing local inflammatory cytokine release and further T cell activation, ultimately resulting in a positive feedback loop that drives alveolar inflammation.

Rogan A. Grant
Luisa Morales-Nebreda
Ziyou Ren
Research11 Jan 2021
Nature

Volume: 590, P: 635-641
Historical dataset details the distribution, extent and form of lost Ostrea edulis reef ecosystems

Ruth H. Thurstan
Hannah McCormick
Philine S. E. zu Ermgassen
ResearchOpen Access05 Nov 2024
Scientific Data

Volume: 11, P: 1-9
Seal Whiskers Vibrate Over Broad Frequencies During Hydrodynamic Tracking

Christin T. Murphy
Colleen Reichmuth
David A. Mann
ResearchOpen Access21 Aug 2017
Scientific Reports

Volume: 7, P: 1-6
To slice or not to slice?

David A. McCormick
Books & Arts01 Jul 2002
Nature Neuroscience

Volume: 5, P: 621
Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Brian W. Kunkle
Benjamin Grenier-Boley
Margaret A. Pericak-Vance
Amendments and Corrections15 Aug 2019
Nature Genetics

Volume: 51, P: 1423-1424
3D ink-extrusion additive manufacturing of CoCrFeNi high-entropy alloy micro-lattices

Additive manufacturing of high entropy alloys is still an emerging field that usually relies on expensive pre-alloyed powders. Here, the authors develop a method to 3D ink-print a CoCrFeNi high entropy alloy using inexpensive blended oxide nanopowders, hydrogen reduction, and sintering.

Christoph Kenel
Nicola P. M. Casati
David C. Dunand
ResearchOpen Access22 Feb 2019
Nature Communications

Volume: 10, P: 1-8
One thousand plant transcriptomes and the phylogenomics of green plants

The One Thousand Plant Transcriptomes Initiative provides a robust phylogenomic framework for examining green plant evolution that comprises the transcriptomes and genomes of diverse species of green plants.

James H. Leebens-Mack
Michael S. Barker
Gane Ka-Shu Wong
ResearchOpen Access23 Oct 2019
Nature

Volume: 574, P: 679-685
POST MORTEM PULMONARY ARTERIAL INJECTION STUDIES IN HYALINE MEMBRANE DISEASE

J F O'Connor
David Ingall
Robert Klein
Research01 Apr 1974
Pediatric Research

Volume: 8, P: 448
Measurement of the generalized spin polarizabilities of the neutron in the low-Q² region

Measurements of observables sensitive to the neutron’s spin precession are extended to a regime that probes distances of the size of the nucleon. They are found to disagree with predictions from chiral effective field theory.

Vincent Sulkosky
Chao Peng
Lingyan Zhu
Research31 May 2021
Nature Physics

Volume: 17, P: 687-692
Male–female communication triggers calcium signatures during fertilization in Arabidopsis

Fertilization involves species-specific interaction and eventually fusion of two gametic cells, and calcium signalling plays a key role in this process. Here, the authors monitor the changes in intracellular calcium that take place during fertilization of flowering plants and point to specific signatures associated with specific steps of the process.

Philipp Denninger
Andrea Bleckmann
Guido Grossmann
ResearchOpen Access22 Aug 2014
Nature Communications

Volume: 5, P: 1-12
A Single Intramuscular Dose of Ceftriaxone Changes Nasopharyngeal Bacterial Flora in Children with Acute Otitis Media (AOM) † 678

Kokab A Saeed
Terho Heikkinen
Tasnee Chonmaitree
Research01 Apr 1998
Pediatric Research

Volume: 43, P: 118
An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy

Carla Heise
Terry Hermiston
David Kirn
Research01 Oct 2000
Nature Medicine

Volume: 6, P: 1134-1139
Quantum-enhanced sensing of a single-ion mechanical oscillator

Number-state superpositions of the harmonic motion of a trapped beryllium ion are used to measure the oscillation frequency with quantum-enhanced sensitivity, achieving a mode-frequency uncertainty of about 10⁻⁶.

Katherine C. McCormick
Jonas Keller
Dietrich Leibfried
Research22 Jul 2019
Nature

Volume: 572, P: 86-90
Cell-type-specific metabolic labeling of nascent proteomes in vivo

Proteomes of distinct cell types in the brains of live mice are labeled and quantitated with a genetically encoded non-canonical amino-acid labeling method and click chemistry.

Beatriz Alvarez-Castelao
Christoph T Schanzenbächer
Erin M Schuman
Research06 Nov 2017
Nature Biotechnology

Volume: 35, P: 1196-1201
CONTROL OF GLUCONEOGENESIS IN THE BABOON FETUS

Lynne L Levitsky
John B Paton
Audrey L Paton
Research01 Apr 1984
Pediatric Research

Volume: 18, P: 296
Killing time for cancer cells

Shoshana Klein
Frank McCormick
Alexander Levitzki
Reviews20 Jun 2005
Nature Reviews Cancer

Volume: 5, P: 573-580
DIAGNOSTIC EFFICACY OF THE TOTAL PERIPHERAL WBC COUNT IN CHILDREN SUSPECTED OF CNS INFECTION

Robert M Lembo
David H Rubin
Paul L McCarthy
Research01 Apr 1987
Pediatric Research

Volume: 21, P: 285
Sensitivity and specificity of blood-fluid levels for oral anticoagulant-associated intracerebral haemorrhage

Abeer Almarzouki
Duncan Wilson
David J. Werring
ResearchOpen Access23 Sept 2020
Scientific Reports

Volume: 10, P: 1-11
657 EFFECTS OF TPN ON INTESTINAL DEVELOPMENT

Robert M Goldstein
David L Dudgeon
Paul W Niemiec
Research01 Apr 1985
Pediatric Research

Volume: 19, P: 220
Replicative adenoviruses for cancer therapy

Ramon Alemany
Cristina Balagué
David T. Curiel
Reviews01 Jul 2000
Nature Biotechnology

Volume: 18, P: 723-727
Efficacy of a replication-competent adenovirus (ONYX-015) following intratumoral injection: Intratumoral spread and distribution effects

Carla C Heise
Angelica Williams
David H Kirn
Research06 Dec 1999
Cancer Gene Therapy

Volume: 6, P: 499-504
Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways

Christian Rommel
Sue C. Bodine
David J. Glass
Research05 Oct 2001
Nature Cell Biology

Volume: 3, P: 1009-1013
Serum myeloperoxidase concentration in a healthy population: biological variations, familial resemblance and new genetic polymorphisms

Aline Hoy
David Trégouët
Sophie Visvikis
Research19 Oct 2001
European Journal of Human Genetics

Volume: 9, P: 780-786
Natural history of retinopathy of prematurity: A prospective study

Alistair R Fielder
David E Shaw
Yin K Ng
Research01 May 1992
Eye

Volume: 6, P: 233-242
Testosterone Suppression of CRH-Stimulated Cortisol in Men

David R Rubinow
Catherine A Roca
Lynnette Nieman
Research20 Apr 2005
Neuropsychopharmacology

Volume: 30, P: 1906-1912
S-RNase uptake by compatible pollen tubes in gametophytic self-incompatibility

Doan-Trung Luu
Xike Qin
Mario Cappadocia
Research05 Oct 2000
Nature

Volume: 407, P: 649-651
Feeding Preterm Infants After Hospital Discharge: 2. Effect of Diet on Nutrient Intake and Body Composition 1507a

Richard J Cooke
Kenny McCormick
Keith Faulkner
Research01 Apr 1998
Pediatric Research

Volume: 43, P: 258
In situ analyses of genome instability in breast cancer

Koei Chin
Carlos Ortiz de Solorzano
Stephen J Lockett
Research08 Aug 2004
Nature Genetics

Volume: 36, P: 984-988
Determinants of woody cover in African savannas

Mahesh Sankaran
Niall P. Hanan
Nick Zambatis
Research08 Dec 2005
Nature

Volume: 438, P: 846-849
Production of Transgenic Soybean Plants Using Agrobacterium-Mediated DNA Transfer

Maud A. W. Hinchee
Dannette V. Connor-Ward
Robert B. Horsch
Research01 Aug 1988
Bio/Technology

Volume: 6, P: 915-922
Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells

Liang You
Biao He
David M Jablons
Research21 Jun 2004
Oncogene

Volume: 23, P: 6170-6174

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