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Showing 1–6 of 6 results
Advanced filters: Author: Davinia Salvachúa Clear advanced filters

  • Oxidative catalytic depolymerization of polystyrene (PS) can produce benzoic acid, but the annual consumption of benzoic acid is ~40 times lower than PS, so benzoic acid should be converted to higher-volume chemicals for the process to be viable. Here, the authors report a hybrid chemical and biological process that uses PS as feedstock for production of adipic acid, a high-volume co-monomer for nylon 6,6, via benzoic acid.

    • Hyunjin Moon
    • Jason S. DesVeaux
    • Gregg T. Beckham
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-14

  • Cultivation of white-rot fungi in distinct incubation conditions and in the presence of a lignin-related aromatic compound induces significant metabolic changes on aromatic catabolic pathways in the transcriptome, proteome, lipidome, and metabolome.

    • Lummy Maria Oliveira Monteiro
    • Carlos del Cerro
    • Davinia Salvachúa
    ResearchOpen Access
    Communications Biology
    Volume: 8, P: 1-15

  • Engineered polyketide synthases (PKSs) have great potential as biocatalysts for the synthesis of chemically challenging molecules. Here the authors show a retrobiosynthesis approach to design and construct PKSs to produce a series of valerolactams for biopolymer production.

    • Namil Lee
    • Matthias Schmidt
    • Jay D. Keasling
    ResearchOpen Access
    Nature Catalysis
    Volume: 8, P: 389-402

  • Muconic acid is a platform chemical with wide industrial applicability. Here, the authors report efficient muconate production from glucose and xylose by engineered Pseudomonas putida strain using adaptive laboratory evolution, metabolic modeling, and rational strain engineering strategies.

    • Chen Ling
    • George L. Peabody
    • Gregg T. Beckham
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-14

  • Lignin conversion to higher value products is essential to the economic viability of lignocellulosic biorefineries. Here, the authors demonstrate the bioconversion of alkali pretreated lignin to itaconic acid by dynamic two stage fermentation using a signal-amplified nitrogen-limitation biosensor.

    • Joshua R. Elmore
    • Gara N. Dexter
    • Adam M. Guss
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-12