Here, the authors show that the Saccharibacteria Nanosynbacter lyticus strain TM7x elicits limited immune activation in the oral cavity, and binds to gingival epithelial cells via a T4P-dependent mechanism, leading to clustering of TLR2 receptors and subsequent caveolin-mediated endocytosis.
- Deepak Chouhan
- Alex S. Grossman
- Batbileg Bor
