Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–4 of 4 results
Advanced filters: Author: Demin Ren Clear advanced filters

  • C(sp3)–H fluoroalkylation of bioactive molecules is a challenge. Now, a scalable and site-selective allylic fluoroalkylation of terpenes and olefins has been developed using a cobaloxime catalyst. Mechanistic studies reveal the process probably proceeds through halogen-atom transfer and hydrogen-atom transfer steps.

    • Shengchun Wang
    • Demin Ren
    • Aiwen Lei
    Research
    Nature Synthesis
    Volume: 2, P: 1202-1210

  • Allylic amination of unactivated alkenes with aliphatic amines is a long-standing synthetic challenge in organic chemistry. This is now accomplished in an oxidant-free, site-selective process by using a combination of a photocatalyst and cobalt complex for the coupling of olefins and alkyl amines with hydrogen evolution.

    • Shengchun Wang
    • Yiming Gao
    • Aiwen Lei
    Research
    Nature Catalysis
    Volume: 5, P: 642-651

  • Simultaneous functionalization of reactive and inert remote sites presents a powerful approach to access complex molecules, yet it is hindered by precise remote C(sp3)–H activation. Now, the accurate translocation of functional groups and remote C–H desaturation has been achieved in parallel through combining functional group migration and cobalt-promoted hydrogen atom transfer.

    • Shengchun Wang
    • Xu Luo
    • Aiwen Lei
    Research
    Nature Chemistry
    Volume: 16, P: 1621-1629