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Advanced filters: Author: Devashish Sen Clear advanced filters

  • Itaconate is shown to non-covalently inhibit the antioxidant enzyme peroxiredoxin 5 in macrophages, thereby modulating the production of mitochondrial peroxide and enhancing the type I interferon production.

    • Tomas Paulenda
    • Barbora Echalar
    • Maxim N. Artyomov
    Research
    Nature Metabolism
    Volume: 7, P: 1183-1203