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Showing 1–2 of 2 results
Advanced filters: Author: Diya Vyas Clear advanced filters
  • Microglial states throughout remyelination are incompletely understood. Here, the authors show that microglia form several states during the early stages of remyelination that coalesce into a partially resolved state that is dysregulated with age.

    • Sameera Zia
    • Marianela E. Traetta
    • Jason R. Plemel
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-24
  • The mechanisms of intratumoral subtype heterogeneity in pancreatic ductal adenocarcinoma (PDAC) remain unclear. Here, the authors analyse PDAC tumours and preclinical models using multi-omics and imaging; they demonstrate that AP1 dichotomy influences tumor plasticity, heterogeneity, and immune response, with potential therapeutic implications.

    • Lukas Klein
    • Mengyu Tu
    • Shiv K. Singh
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-19