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  • Clarke et al. identify chromatin factor ZNF280A, which is recruited to damaged chromatin where it promotes long-range DNA-end resection. Loss of ZNF280A is linked to genome instability in patients with 22q11.2 distal deletion syndrome.

    • Thomas L. Clarke
    • Hyo Min Cho
    • Raul Mostoslavsky
    Research
    Nature Cell Biology
    Volume: 27, P: 1006-1020