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Showing 1–2 of 2 results
Advanced filters: Author: Duda Kvitsiani Clear advanced filters

  • Neural basis of decision-making is not fully understood. Here authors show that mouse prefrontal neurons encode history-specific rewards and choices. However, their influence is gated by task structure and timing, affecting decisions primarily in variable interval tasks and when temporal delays separate events.

    • Junior Samuel Lopez-Yepez
    • Anna Barta
    • Duda Kvitsiani
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-21

  • Cortical inhibitory interneurons expressing vasoactive intestinal polypeptide (VIP) are shown to specialize in suppressing the activity of other inhibitory interneurons and are activated by reinforcement signals, thus increasing the activity of excitatory neurons by releasing them from inhibition; these results reveal a cell-type-specific microcircuit that tunes cortical activity under certain behavioural conditions.

    • Hyun-Jae Pi
    • Balázs Hangya
    • Adam Kepecs
    Research
    Nature
    Volume: 503, P: 521-524