T cells derived from stem cells can be harnessed for regenerative medicine and cancer immunotherapy, but current technologies limit production and translation. Here, the authors present a serum-free, stromal-cell free DLL4-coated microbead method for the scalable production of T-lineage cells from multiple sources of stem cells.
- Ashton C. Trotman-Grant
- Mahmood Mohtashami
- Juan Carlos Zúñiga-Pflücker