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Molecular Psychiatry (1)

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Showing 1–3 of 3 results

Advanced filters: Author: Eesha Sharma Clear advanced filters

High-throughput DNA melt measurements enable improved models of DNA folding thermodynamics

DNA thermodynamics underlies many biological and biotechnological applications but is challenging to accurately predict. Here, the authors develop a high-throughput DNA melting method and improve computational models for predicting DNA folding energies from sequence data.

Yuxi Ke
Eesha Sharma
William J. Greenleaf
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-19
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics

The authors develop an RNA sequencing-based platform, PERSIST-seq, to simultaneously delineate in-cell mRNA stability, ribosome load, and in-solution stability of a diverse mRNA library to derive design principles for improved mRNA therapeutics.

Kathrin Leppek
Gun Woo Byeon
Rhiju Das
ResearchOpen Access22 Mar 2022
Nature Communications

Volume: 13, P: 1-22
The Consortium on Vulnerability to Externalizing Disorders and Addictions (c-VEDA): an accelerated longitudinal cohort of children and adolescents in India

Yuning Zhang
Nilakshi Vaidya
Bhavana B R
Reviews12 Mar 2020
Molecular Psychiatry

Volume: 25, P: 1618-1630