Dowling-Cullen, Fahey et al., describe the clinical, laboratory, and epidemiologic features of a case of monkeypox virus clade Ia infection detected in Dublin, Ireland. Phylogenetic analysis and APOBEC3-associated mutation profiling place the viral genome obtained from this case in an evolving cluster of infections in the Democratic Republic of the Congo, drawing attention to recent changes in the epidemiology of this virus with evidence supporting sustained human-to-human transmission.
- Cian Dowling-Cullen
- Laura Fahey
- Derval Igoe
