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Communications Biology (1)

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Modelling arrhythmogenic cardiomyopathy fattyfibro pathology with PKP2-deficient epicardial cells derived from human iPSCs

Arrhythmogenic cardiomyopathy modelling using patient-specific IPSC-derived epicardial cells and the corresponding CRISPR/Cas9-corrected cells reveals signalling pathways related to Wnt, Rho GTPase, and IGF involved in fattyfibro remodelling.

Sadia L. Falana
Sobhi G. Kazmouz
Jared M. Churko
ResearchOpen Access27 Oct 2025
Communications Biology

Volume: 8, P: 1-15

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Modelling arrhythmogenic cardiomyopathy fattyfibro pathology with PKP2-deficient epicardial cells derived from human iPSCs

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