Nature Search

Multi-omics reveals nitrogen dynamics associated with soil microbial blooms during snowmelt

Soil microbial populations bloom and then die-off in ecosystems with seasonal snowpack. This study showed that distinct taxa utilize different N sources for growth or energy during the microbial bloom and alter the fate of N after snowmelt.

Patrick O. Sorensen
Ulas Karaoz
Eoin L. Brodie
ResearchOpen Access27 Jan 2026
Nature Microbiology

Volume: 11, P: 359-374
A phase I/II trial of WT1-specific TCR gene therapy for patients with acute myeloid leukemia and active disease post-allogeneic hematopoietic cell transplantation: skewing towards NK-like phenotype impairs T cell function and persistence

Relapsed and/or refractory acute myeloid leukemia (AML) postallogeneic hematopoietic cell transplantation has limited treatment options. Here the authors report the clinical results and immune correlates of a phase I/II trial of adoptively transferred virus-specific donor CD8 + T cells engineered to express a WT1-specific T cell receptor in patients with acute myeloid leukemia and active disease post-allogeneic hematopoietic cell transplantation.

Francesco Mazziotta
Lauren E. Martin
Aude G. Chapuis
ResearchOpen Access05 Jun 2025
Nature Communications

Volume: 16, P: 1-20
TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression

TET2 and GATA2 are two frequently co-mutated genes in CEBPA double mutated acute myeloid leukemia (AML). Here the authors show that the underlying mechanism for this cooccurrence is for TET2 loss-of-function mutation to counteract the increase in GATA2 expression, which is disadvantageous to these type of AML cells.

Elizabeth Heyes
Anna S. Wilhelmson
Bo T. Porse
ResearchOpen Access04 Oct 2023
Nature Communications

Volume: 14, P: 1-18
The Imprinted Gene Peg3 Is Not Essential for Tumor Necrosis Factor α Signaling

Elizabeth C Ledgerwood
Stephen O'Rahilly
M Azim Surani
Research01 Oct 2000
Laboratory Investigation

Volume: 80, P: 1509-1511
Biomolecular condensation of NUP98 fusion proteins drives leukemogenic gene expression

A mass spectrometry–based approach is used to investigate the mechanisms by which different NUP98 fusion proteins cause leukemia, revealing that the fusion proteins share common interactors and alter the composition of nuclear condensates.

Stefan Terlecki-Zaniewicz
Theresa Humer
Florian Grebien
Research21 Jan 2021
Nature Structural & Molecular Biology

Volume: 28, P: 190-201
Swarm learning for decentralized artificial intelligence in cancer histopathology

A decentralized, privacy-preserving machine learning framework used to train a clinically relevant AI system identifies actionable molecular alterations in patients with colorectal cancer by use of routine histopathology slides collected in real-world settings.

Oliver Lester Saldanha
Philip Quirke
Jakob Nikolas Kather
ResearchOpen Access25 Apr 2022
Nature Medicine

Volume: 28, P: 1232-1239
Adding labile carbon to peatland soils triggers deep carbon breakdown

Glucose addition to peatland soils promotes decomposition of older buried carbon through enhanced microbial activity, according to DNA analysis and isotope labelling of peatland soil.

Sumudu Rajakaruna
Ghiwa Makke
Malak M. Tfaily
ResearchOpen Access27 Dec 2024
Communications Earth & Environment

Volume: 5, P: 1-14
The frequency of pathogenic variation in the All of Us cohort reveals ancestry-driven disparities

A comparison of the frequency of pathogenic mutations in 73 genes in the All of Us cohort highlights the differences in pathogenic variation attributed to ancestry.

Eric Venner
Karynne Patterson
Miriam Vos
ResearchOpen Access19 Feb 2024
Communications Biology

Volume: 7, P: 1-11
Diverse electron carriers drive syntrophic interactions in an enriched anaerobic acetate-oxidizing consortium

Elizabeth A. McDaniel
Matthew Scarborough
Ryan M. Ziels
ResearchOpen Access25 Oct 2023
The ISME Journal

Volume: 17, P: 2326-2339
ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

Ali Abbas
Sheryl Ann Abdukahil
Luis Felipe Reyes
ResearchOpen Access30 Jul 2022
Scientific Data

Volume: 9, P: 1-22
Molecular genetic analysis of central nervous system germ cell tumors with comparative genomic hybridization

Dominik T Schneider
Susanne Zahn
Elizabeth J Perlman
Research07 Apr 2006
Modern Pathology

Volume: 19, P: 864-873

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Multi-omics reveals nitrogen dynamics associated with soil microbial blooms during snowmelt

A phase I/II trial of WT1-specific TCR gene therapy for patients with acute myeloid leukemia and active disease post-allogeneic hematopoietic cell transplantation: skewing towards NK-like phenotype impairs T cell function and persistence

TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression

The Imprinted Gene Peg3 Is Not Essential for Tumor Necrosis Factor α Signaling

Biomolecular condensation of NUP98 fusion proteins drives leukemogenic gene expression

Swarm learning for decentralized artificial intelligence in cancer histopathology

Adding labile carbon to peatland soils triggers deep carbon breakdown

The frequency of pathogenic variation in the All of Us cohort reveals ancestry-driven disparities

Diverse electron carriers drive syntrophic interactions in an enriched anaerobic acetate-oxidizing consortium

ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

Molecular genetic analysis of central nervous system germ cell tumors with comparative genomic hybridization

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