IL-2 complexes (IL-2c) which are IL-2 complexed with anti-IL-2 can be used to promote T cell function. Here authors use IL2c in addition to checkpoint inhibitors and irradiation to increase anti-tumour T cell responses and promote tumour rejection in mouse cancer models.
- Kateryna Onyshchenko
- Ren Luo
- Gabriele Niedermann
