Cerebral malaria (CM) is a severe complication of Plasmodium falciparum infection. Here the authors show that methylene blue treatment reverses brainstem damage in rhesus macaque CM and identify neutrophil-linked genes as potential biomarkers for severe and fatal P. falciparum infection.
- Jing Wen Hang
- Yew Wai Leong
- Benoît Malleret