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Showing 1–10 of 10 results

Advanced filters: Author: Erica Herzog Clear advanced filters

Aberrant cellular communities underlying disease heterogeneity in chronic obstructive pulmonary disease

This study uses single-nucleus RNA sequencing to analyze lung tissue from 141 individuals with chronic obstructive pulmonary disease. Distinct patterns of spatially resolved changes in cell composition and cell states that correlate with clinical features are highlighted.

Yuening Zhang
Huanhuan Wei
Maor Sauler
ResearchOpen Access23 Jan 2026
Nature Genetics

P: 1-16
Fibrocytes: emerging effector cells in chronic inflammation

Erica Herzog and colleagues put forward the opinion that fibrocytes, a little-studied population of monocyte-derived cells that have properties of both macrophages and fibroblasts, have unique roles in chronic inflammation that warrant further study.

Ronald A. Reilkoff
Richard Bucala
Erica L. Herzog
Reviews20 May 2011
Nature Reviews Immunology

Volume: 11, P: 427-435
Integrated computational and experimental pipeline for quantifying local cell–matrix interactions

Hugh Xiao
Ryan Y. Nguyen
Michael Mak
ResearchOpen Access12 Aug 2021
Scientific Reports

Volume: 11, P: 1-11
Fibroblast A20 governs fibrosis susceptibility and its repression by DREAM promotes fibrosis in multiple organs

A20 gene variants are linked with systemic sclerosis (SS), but the mechanisms are unclear. Here, the authors show that A20 expression is reduced in SS skin and lungs, that its ablation in mice induces SS, and that show that fibrosis can be ameliorated by induction of A20.

Wenxia Wang
Swarna Bale
John Varga
ResearchOpen Access26 Oct 2022
Nature Communications

Volume: 13, P: 1-16
Distinct roles of KLF4 in mesenchymal cell subtypes during lung fibrogenesis

The pluripotency factor KLF4 has been described as pro-fibrotic or anti-fibrotic in various diseases. Herein, the authors show that during lung fibrosis, these distinct effects can be attributed to mesenchymal cell-type specific functions of KLF4.

Rachana R. Chandran
Yi Xie
Daniel M. Greif
ResearchOpen Access10 Dec 2021
Nature Communications

Volume: 12, P: 1-17
Author Correction: Fibroblast A20 governs fibrosis susceptibility and its repression by DREAM promotes fibrosis in multiple organs

Wenxia Wang
Swarna Bale
John Varga
Amendments and CorrectionsOpen Access31 Jan 2023
Nature Communications

Volume: 14, P: 1
Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function

Thyroid hormone improves mitochondrial function and dynamics in lung epithelium to reduce pulmonary fibrosis in mice.

Guoying Yu
Argyris Tzouvelekis
Naftali Kaminski
Research04 Dec 2017
Nature Medicine

Volume: 24, P: 39-49
Rational engineering of lung alveolar epithelium

Katherine L. Leiby
Yifan Yuan
Laura E. Niklason
ResearchOpen Access28 Apr 2023
npj Regenerative Medicine

Volume: 8, P: 1-18
RIG-like Helicase Regulation of Chitinase 3-like 1 Axis and Pulmonary Metastasis

Bing Ma
Erica L. Herzog
Jack A. Elias
ResearchOpen Access20 May 2016
Scientific Reports

Volume: 6, P: 1-13
Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype

Susan K Mathai
Mridu Gulati
Erica L Herzog
Research19 Apr 2010
Laboratory Investigation

Volume: 90, P: 812-823